Serum fat-soluble vitamin levels may be related to sudden sensorineural hearing loss.

IF 1.2 4区医学 Q3 OTORHINOLARYNGOLOGY

Acta Oto-Laryngologica Pub Date : 2023-07-01 Epub Date: 2023-07-19 DOI:10.1080/00016489.2023.2220365

Haifeng Zheng, Miao Liu, Hongli Fu, Lidong Zhao

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引用次数: 0

Abstract

Background: Few related studies reported yet the association between vitamins and the onset of sudden sensorineural hearing loss (SSNHL).

Objective: To explore the relationship between the serum levels of fat-soluble vitamins A, D, and E and the risk of SSNHL.

Methods: This retrospective analysis included 310 SSNHL patients and 154 people without risk of hearing loss. The demographic information of all participants like age, gender, body mass index, occupation, cigarette smoking or drinking status, etc. were recorded. The serum levels of vitamins A, D, and E were determined using the electrochemical method.

Results: The results indicated that serum vitamin D levels in SSNHL patients were significantly lower. Vitamin D deficiency was only observed in SSNHL group. Similarly, serum vitamin A levels in female SSNHL patients were significantly lower than the control group. Meanwhile, serum vitamin E levels in male SSNHL patients were significantly lower than the control group.

Conclusion and significance: Our results revealed that the serum levels of fat-soluble vitamins A, D, and E in SSNHL patients were lower than those in the control group with normal hearing, indicating that the decrease of serum fat-soluble vitamins may be related to SSNHL pathogenesis.

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血清脂溶性维生素水平可能与突发性感音神经性听力损失有关。

背景：迄今为止，很少有相关研究报道维生素与突发性感音神经性听力损失（SSNHL）的发病之间的关系。目的：探讨血清脂溶性维生素A、D和E水平与SSNHL风险的关系。方法：本回顾性分析包括310名SSNHL患者和154名无听力损失风险的人。记录所有参与者的人口统计信息，如年龄、性别、体重指数、职业、吸烟或饮酒状况等。使用电化学方法测定血清中维生素A、D和E的水平。结果：SSNHL患者血清维生素D水平明显降低。维生素D缺乏仅在SSNHL组中观察到。同样，女性SSNHL患者的血清维生素A水平显著低于对照组。同时，男性SSNHL患者血清维生素E水平显著低于对照组。结论和意义：SSNHL患者血清脂溶性维生素A、D和E水平低于听力正常的对照组，表明血清脂溶型维生素的降低可能与SSNHL的发病机制有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Oto-Laryngologica 医学-耳鼻喉科学

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

3-6 weeks

期刊介绍： Acta Oto-Laryngologica is a truly international journal for translational otolaryngology and head- and neck surgery. The journal presents cutting-edge papers on clinical practice, clinical research and basic sciences. Acta also bridges the gap between clinical and basic research.