Analysis of Resting Energy Consumption and Its Influencing Factors in Stroke Patients with Severe Neurological Diseases: A Retrospective Clinical Study.

IF 2.2 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Neuroimmunomodulation Pub Date : 2022-01-01 DOI:10.1159/000524719

Hui Feng, Huaping Pan, Wei Yao, Chengyao Mei

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引用次数: 0

Abstract

Background: This study aimed to observe the changes of resting energy metabolism in patients with severe neurological diseases, and to explore the effects of tracheostomy status, stroke severity, and complications on resting energy expenditure (REE) and respiratory quotient (RQ).

Methods: A retrospective study was conducted in 105 patients with neurological rehabilitation who were hospitalized in the Rehabilitation Department of the Affiliated Jiangning Hospital of Nanjing Medical University from August 2018 to October 2021. REE was measured by Italian Cosmed k4b2 indirectly, and white blood cell count and C-reactive protein (CRP) were collected.

Results: Among the 105 patients, there were 18 cases of mild stroke, 45 cases of moderate stroke, and 42 cases of severe stroke. The difference between predicted REE and actual REE among different degrees of stroke patients was statistically significant (p < 0.05); there was no significant difference in RQ values among different degrees of stroke patients (p > 0.05). Hemoglobin, albumin, and body mass index were significantly and positively correlated with predicted REE and actual REE, while CRP was significantly negatively correlated with predicted REE and actual REE. There was no significant difference in predicted REE, actual REE, and RQ between renal insufficiency, type 2 diabetes mellitus, and chronic obstructive pulmonary disease (p > 0.05). The CRP level could affect the REE of stroke patients.

Conclusion: Metabolic vehicle assay has a certain clinical value in accurately evaluating the metabolic needs and feeding level of patients.

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脑卒中合并严重神经系统疾病患者静息能量消耗及其影响因素的回顾性临床研究

背景:本研究旨在观察重症神经系统疾病患者静息能量代谢的变化，探讨气管切开状态、卒中严重程度及并发症对静息能量消耗(REE)和呼吸商(RQ)的影响。方法:对2018年8月至2021年10月南京医科大学附属江宁医院康复科住院的105例神经康复患者进行回顾性研究。采用意大利Cosmed k4b2间接测定REE，采集白细胞计数和c反应蛋白(CRP)。结果:105例患者中，轻度脑卒中18例，中度脑卒中45例，重度脑卒中42例。不同程度脑卒中患者预测REE与实际REE差异有统计学意义(p < 0.05);不同程度脑卒中患者RQ值差异无统计学意义(p > 0.05)。血红蛋白、白蛋白、体重指数与预测REE和实际REE呈显著正相关，CRP与预测REE和实际REE呈显著负相关。肾功能不全、2型糖尿病和慢性阻塞性肺疾病患者预测REE、实际REE、RQ差异无统计学意义(p > 0.05)。CRP水平可影响脑卒中患者的REE。结论:代谢载体法对准确评价患者的代谢需求和摄食水平有一定的临床价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuroimmunomodulation 医学-免疫学

CiteScore

3.60

自引率

4.20%

发文量

审稿时长

>12 weeks

期刊介绍： The rapidly expanding area of research known as neuroimmunomodulation explores the way in which the nervous system interacts with the immune system via neural, hormonal, and paracrine actions. Encompassing both basic and clinical research, ''Neuroimmunomodulation'' reports on all aspects of these interactions. Basic investigations consider all neural and humoral networks from molecular genetics through cell regulation to integrative systems of the body. The journal also aims to clarify the basic mechanisms involved in the pathogenesis of the CNS pathology in AIDS patients and in various neurodegenerative diseases. Although primarily devoted to research articles, timely reviews are published on a regular basis.

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