Utility of Walk Tests in the Progression of Mild COVID-19 Infection at a Tertiary Hospital in North India.

Souradeep Chowdhury, Tamoghna Ghosh, Aastha Goel, Anupam K Singh, Arvind Kumar, Naveet Wig
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Abstract

Introduction: There have been 214 million confirmed cases of COVID-19 worldwide, with a total death tally of 4.4 million. The current study aims to determine the predictive value of various scores in the assessment of progression of mild COVID-19 infection at a tertiary care hospital in North India.

Methods: The study population consisted of adults (age more than 18 years) with a confirmed diagnosis of COVID-19 by RT-PCR on nasopharyngeal specimens. Patients with only mild illness were enrolled. After the patients were admitted to the isolation ward, the presenting history, comorbidity status, vital signs and laboratory parameters were recorded. The 3 and 6 minutes walk test was performed daily from admission till discharge or progression of the severity of COVID- 19, and it was used to calculate Borg Dyspnoea Score (BDS) and National Early Warning Score (NEWS2) scores.

Results: Our study consisted of 50 patients with 34 (68%) males, and the mean (SD) age of the patient population was 28.1 (6.4) years. The most common symptoms were fever, sore throat, and cough. All laboratory parameters were within normal ranges for all the patients. 96% recovered without progression, while only 4% of them progressed to moderate illness. Results of the 3 and 6 minutes walk tests, BDS and NEWS2 scores showed improvement over the course of the hospital stay.

Conclusion: Although the walk tests and the scores improved over time, they failed to predict the disease progression.

步行测试在印度北部一家三级医院轻度COVID-19感染进展中的应用
导语:全球已有2.14亿例COVID-19确诊病例,总死亡人数为440万。目前的研究旨在确定各种评分在评估印度北部三级医院轻度COVID-19感染进展中的预测价值。方法:研究人群为经鼻咽标本RT-PCR确诊为COVID-19的成年人(18岁以上)。只有轻度疾病的患者被纳入研究。患者入住隔离病房后,记录患者的就诊史、合并症、生命体征及实验室参数。从入院到出院或COVID- 19严重程度进展,每天进行3分钟和6分钟步行测试,并用于计算Borg呼吸困难评分(BDS)和国家早期预警评分(NEWS2)评分。结果:我们的研究包括50例患者,其中34例(68%)为男性,患者群体的平均(SD)年龄为28.1(6.4)岁。最常见的症状是发烧、喉咙痛和咳嗽。所有患者的实验室参数均在正常范围内。96%的患者康复无进展,而只有4%的患者进展为中度疾病。3分钟和6分钟步行测试的结果、BDS和NEWS2评分显示在住院期间有所改善。结论:尽管步行测试和得分随着时间的推移而提高,但它们不能预测疾病的进展。
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