Quick drop of platelet counts in children with chronic immune thrombocytopenia after COVID-19 mRNA vaccination: case reports.

IF 2.1 Q4 IMMUNOLOGY

Clinical and Experimental Vaccine Research Pub Date : 2022-09-01 DOI:10.7774/cevr.2022.11.3.290

Giuseppe Lassandro, Francesco Carriero, Valentina Palladino, Giovanni Carlo Del Vecchio, Paola Giordano

引用次数: 1

Abstract

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia. Many viruses and some vaccines have been identified as triggering the autoimmune process, including parvovirus, human immunodeficiency virus, Epstein-Barr virus, rubella, and measles. However, ITP in association with coronavirus disease 2019 (COVID-19) vaccination has not been reported so far. We describe the cases of two young girls affected by ITP presenting a quick reduction of platelet count after receiving Pfizer-BioNTech COVID-19 vaccine.

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慢性免疫性血小板减少症患儿接种COVID-19 mRNA后血小板计数快速下降:病例报告

免疫性血小板减少症(ITP)是一种以孤立性血小板减少为特征的自身免疫性疾病。许多病毒和一些疫苗已被确定为触发自身免疫过程，包括细小病毒、人类免疫缺陷病毒、爱泼斯坦-巴尔病毒、风疹和麻疹。然而，到目前为止，与2019冠状病毒病(COVID-19)疫苗接种相关的ITP尚未报道。我们描述了两例受ITP影响的年轻女孩在接受辉瑞- biontech COVID-19疫苗后血小板计数迅速减少的病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Experimental Vaccine Research IMMUNOLOGY-

CiteScore

3.70

自引率

3.70%

发文量

审稿时长

8 weeks

期刊介绍： Clin Exp Vaccine Res, the official English journal of the Korean Vaccine Society, is an international, peer reviewed, and open-access journal. It covers all areas related to vaccines and vaccination. Clin Exp Vaccine Res publishes editorials, review articles, special articles, original articles, case reports, brief communications, and correspondences covering a wide range of clinical and experimental subjects including vaccines and vaccination for human and animals against infectious diseases caused by viruses, bacteria, parasites and tumor. The scope of the journal is to disseminate information that may contribute to elaborate vaccine development and vaccination strategies targeting infectious diseases and tumors in human and animals. Relevant topics range from experimental approaches to (pre)clinical trials for the vaccine research based on, but not limited to, basic laboratory, translational, and (pre)clinical investigations, epidemiology of infectious diseases and progression of all aspects in the health related issues. It is published printed and open accessed online issues (https://ecevr.org) two times per year in 31 January and 31 July. Clin Exp Vaccine Res is linked to many international databases and is made freely available to institutions and individuals worldwide