VEXAS syndrome: an adult-onset monogenic autoinflammatory disease with many unanswered questions.

Abstract

José Hernández-Rodríguez1,2,3,4 ID , Jakub Nieścieruk5 ID , Maria Maślińska4,5 ID 1Clinical Unit of Autoinflammatory Diseases and Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clínic of Barcelona, Spain 2Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain 3Center of the European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) 4Center of the European Reference Network (ERN) on Connective Tissue and Musculoskeletal Diseases (ReCONNET) 5Early Arthritis Clinic, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland