{"title":"Modified polymer membranes for the removal of pharmaceutical active compounds in wastewater and its mechanism-A review.","authors":"Anisa Ratnasari","doi":"10.1080/21655979.2023.2252234","DOIUrl":null,"url":null,"abstract":"<p><p>Membrane technology can play a suitable role in removing pharmaceutical active compounds since it requires low energy and simple operation. Even though membrane technology has progressed for wastewater applications nowadays, modifying membranes to achieve the strong desired membrane performance is still needed. Thus, this study overviews a comprehensive insight into the application of modified polymer membranes to remove pharmaceutical active compounds from wastewater. Biotoxicity of pharmaceutical active compounds is first prescribed to gain deep insight into how membranes can remove pharmaceutical active compounds from wastewater. Then, the behavior of the diffusion mechanism can be concisely determined using mass transfer factor model that represented by β and B with value up to 2.004 g h mg<sup>-1</sup> and 1.833 mg g<sup>-1</sup> for organic compounds including pharmaceutical active compounds. The model refers to the adsorption of solute to attach onto acceptor sites of the membrane surface, external mass transport of solute materials from the bulk liquid to the membrane surface, and internal mass transfer to diffuse a solute toward acceptor sites of the membrane surface with evidenced up to 0.999. Different pharmaceutical compounds have different solubility and relates to the membrane hydrophilicity properties and mechanisms. Ultimately, challenges and future recommendations have been presented to view the future need to enhance membrane performance regarding fouling mitigation and recovering compounds. Afterwards, the discussion of this study is projected to play a critical role in advance of better-quality membrane technologies for removing pharmaceutical active compounds from wastewater in an eco-friendly strategy and without damaging the ecosystem.</p>","PeriodicalId":8919,"journal":{"name":"Bioengineered","volume":null,"pages":null},"PeriodicalIF":4.2000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ff/f6/KBIE_14_2252234.PMC10506444.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioengineered","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1080/21655979.2023.2252234","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Membrane technology can play a suitable role in removing pharmaceutical active compounds since it requires low energy and simple operation. Even though membrane technology has progressed for wastewater applications nowadays, modifying membranes to achieve the strong desired membrane performance is still needed. Thus, this study overviews a comprehensive insight into the application of modified polymer membranes to remove pharmaceutical active compounds from wastewater. Biotoxicity of pharmaceutical active compounds is first prescribed to gain deep insight into how membranes can remove pharmaceutical active compounds from wastewater. Then, the behavior of the diffusion mechanism can be concisely determined using mass transfer factor model that represented by β and B with value up to 2.004 g h mg-1 and 1.833 mg g-1 for organic compounds including pharmaceutical active compounds. The model refers to the adsorption of solute to attach onto acceptor sites of the membrane surface, external mass transport of solute materials from the bulk liquid to the membrane surface, and internal mass transfer to diffuse a solute toward acceptor sites of the membrane surface with evidenced up to 0.999. Different pharmaceutical compounds have different solubility and relates to the membrane hydrophilicity properties and mechanisms. Ultimately, challenges and future recommendations have been presented to view the future need to enhance membrane performance regarding fouling mitigation and recovering compounds. Afterwards, the discussion of this study is projected to play a critical role in advance of better-quality membrane technologies for removing pharmaceutical active compounds from wastewater in an eco-friendly strategy and without damaging the ecosystem.
膜技术可以在去除药物活性化合物方面发挥适当的作用,因为它需要低能量和简单的操作。尽管如今膜技术在废水应用中取得了进展,但仍需要对膜进行改性以获得所需的强膜性能。因此,本研究综述了改性聚合物膜在去除废水中药物活性化合物方面的应用。药物活性化合物的生物毒性是为了深入了解膜如何从废水中去除药物活性化合物而首次提出的。然后,使用以β和B表示的传质因子模型,可以简明地确定扩散机制的行为,其值高达2.004 g h mg-1和1.833 mg g-1用于包括药物活性化合物的有机化合物。该模型指的是溶质吸附到膜表面的受体位点上,溶质材料从本体液体到膜表面上的外部质量传输,以及溶质向膜表面受体位点扩散的内部质量转移,证明高达0.999。不同的药物化合物具有不同的溶解度,并与膜的亲水性性质和机理有关。最终,提出了挑战和未来的建议,以考虑未来在减轻污染和回收化合物方面提高膜性能的需要。之后,本研究的讨论预计将在推进更高质量的膜技术方面发挥关键作用,以环保的策略从废水中去除药物活性化合物,而不会破坏生态系统。
期刊介绍:
Bioengineered provides a platform for publishing high quality research on any aspect of genetic engineering which involves the generation of recombinant strains (both prokaryote and eukaryote) for beneficial applications in food, medicine, industry, environment and bio-defense.