Evaluation of effectiveness of pharmacological treatment in pelvic congestion syndrome.

IF 1.2 4区 医学 Q3 OBSTETRICS & GYNECOLOGY
Karolina B Gora, Slawomir Wozniak
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引用次数: 0

Abstract

Pelvic congestion syndrome (PCS) is a pain syndrome characterized by positional pelvic pain and is associated with pelvic and vulvar varicosities as well as symptoms of dyspareunia and postcoital pain. Since the etiology of PCS is complex, the treatment should be individualized. Despite both pharmacological and interventional methods being used, there is significant predominance of minimally invasive therapies e.g. embolization. The study considers the answer to the question of whether pharmacological therapy is altogether effective. Using a combination of keywords, a PubMed search was performed for the years 1987-2022. The relevant articles were appointed and included in this narrative review. Despite the multitude of alternatives for pharmacological treatment, the systemic side effects of the medications used, as well as the interactions between drugs, affect patients' compliance and persistence. Furthermore, the quality of the currently existing evidence, considering the efficacy of the given substances, is low. Because of the adverse effects and thus the limited drug administration period, there is currently insufficient research on long-term effectiveness of the PCS pharmacological treatment. Therefore, prospective, comparative studies with larger patient population sizes are necessary to provide the possibility of efficient pharmacological therapy.

盆腔充血综合征的药物治疗效果评价。
盆腔充血综合征(PCS)是一种以位置性盆腔疼痛为特征的疼痛综合征,与盆腔和外阴静脉曲张以及性交困难和性交后疼痛相关。由于PCS的病因复杂,治疗应个体化。尽管药物和介入治疗方法都被使用,但微创治疗(如栓塞)仍占明显优势。这项研究考虑了药物治疗是否完全有效的问题的答案。使用关键词组合,对1987-2022年的PubMed进行了搜索。有关文章已被指定并列入本叙述性审查。尽管有多种替代药物治疗,但所使用药物的全身副作用以及药物之间的相互作用影响了患者的依从性和持久性。此外,考虑到给定物质的功效,目前现有证据的质量很低。由于其不良反应和给药周期有限,目前对PCS药物治疗的长期有效性研究不足。因此,有必要对更大的患者群体进行前瞻性的比较研究,以提供有效的药物治疗的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Ginekologia polska
Ginekologia polska OBSTETRICS & GYNECOLOGY-
CiteScore
2.00
自引率
15.40%
发文量
317
审稿时长
4-8 weeks
期刊介绍: Ginekologia Polska’ is a monthly medical journal published in Polish and English language. ‘Ginekologia Polska’ will accept submissions relating to any aspect of gynaecology, obstetrics and areas directly related. ‘Ginekologia Polska’ publishes original contributions, comparative works, case studies, letters to the editor and many other categories of articles.
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