Methodological Issues with Head and Neck Cancer Prognostic Risk Prediction Models.

IF 0.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Community dental health Pub Date : 2023-11-30 DOI:10.1922/CDH_00015Ghanati09

H Ghanati, S Madathil, M Al-Tamimi, Z Al Asmar, M Morris, B Nicolau

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引用次数: 0

Abstract

Objective: Prognostic risk prediction models estimate the probability of developing head and neck cancer (HNC), providing valuable information for managing the disease. While different prognostic HNC risk prediction models have been developed worldwide, a comprehensive evaluation of their methods is lacking. We conducted a scoping review with a critical assessment aiming to identify the methodological strengths and limitations of HNC risk prediction models.

Method: We searched Medline, Embase, Scopus, Web of Science, and CAB Abstracts databases and included full-text-available peer-reviewed published papers on developing or validating a prognostic HNC risk prediction model. Study quality was appraised using the PROBAST tool.

Results: Nine papers were included. Although all had a high risk of bias, mainly in the analysis domain, only two studies had high concerns about clinical applicability.

Conclusion: Currently published studies provide insufficient information on methods, making it difficult to judge the models' quality and applicability. Future investigations should follow the guidelines in reporting the prediction modelling studies.

查看原文本刊更多论文

头颈癌预后风险预测模型的方法学问题。

目的:建立预后风险预测模型，评估头颈癌(HNC)发生的概率，为疾病管理提供有价值的信息。虽然世界各地已经开发了不同的HNC预后风险预测模型，但缺乏对其方法的全面评估。我们进行了范围审查，并进行了批判性评估，旨在确定HNC风险预测模型的方法学优势和局限性。方法:我们检索了Medline、Embase、Scopus、Web of Science和CAB Abstracts数据库，并收录了有关开发或验证预后性HNC风险预测模型的同行评审论文全文。使用PROBAST工具评价研究质量。结果:共纳入9篇论文。虽然所有研究都存在高偏倚风险，主要是在分析领域，但只有两项研究对临床适用性有高度关注。结论:目前已发表的研究对方法的信息不足，难以判断模型的质量和适用性。未来的调查应遵循报告预测模型研究的指导方针。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Community dental health 医学-牙科与口腔外科

CiteScore

2.20

自引率

11.80%

发文量

审稿时长

6-12 weeks

期刊介绍： The journal is concerned with dental public health and related subjects. Dental public health is the science and the art of preventing oral disease, promoting oral health, and improving the quality of life through the organised efforts of society. The discipline covers a wide range and includes such topics as: -oral epidemiology- oral health services research- preventive dentistry - especially in relation to communities- oral health education and promotion- clinical research - with particular emphasis on the care of special groups- behavioural sciences related to dentistry- decision theory- quality of life- risk analysis- ethics and oral health economics- quality assessment. The journal publishes scientific articles on the relevant fields, review articles, discussion papers, news items, and editorials. It is of interest to dentists working in dental public health and to other professionals concerned with disease prevention, health service planning, and health promotion throughout the world. In the case of epidemiology of oral diseases the Journal prioritises national studies unless local studies have major methodological innovations or information of particular interest.