Neurobiological and pathophysiological concepts of Christfried Jakob (1866–1956) on language and aphasia: An English translation of two communications [1910,1932] and a modern perspective

IF 2.7 4区医学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of chemical neuroanatomy Pub Date : 2023-09-17 DOI:10.1016/j.jchemneu.2023.102341

Maria E. Vasilopoulou , Lazaros C. Triarhou

{"title":"Neurobiological and pathophysiological concepts of Christfried Jakob (1866–1956) on language and aphasia: An English translation of two communications [1910,1932] and a modern perspective","authors":"Maria E. Vasilopoulou , Lazaros C. Triarhou","doi":"10.1016/j.jchemneu.2023.102341","DOIUrl":null,"url":null,"abstract":"<div><p><span>The aim of the present article is to preserve, in English translation, two historical communications on aphasia and the pathophysiology of language by the neurobiologist Christfried Jakob (1866–1956) of Buenos Aires, and to place them in a modern perspective. The morphofunctional basis of human language and its pathology occupied Jakob’s mind over three decades. His synthetic conclusions were based on the neuropathological examination of dozens of aphasic cases from the Hospital de Las Mercedes and the National Women’s Psychiatric Hospital between 1906 and 1936. Special mention is made of the role of the </span>cerebellum<span><span>, the thalamus, and their connections with the </span>cerebral cortex, and the language network. Current research and imaging studies support and elaborate that which Jacob presented so many years ago; many of his analyses and ideas are informative and remain relevant today.</span></p></div>","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"133 ","pages":"Article 102341"},"PeriodicalIF":2.7000,"publicationDate":"2023-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of chemical neuroanatomy","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0891061823001114","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

The aim of the present article is to preserve, in English translation, two historical communications on aphasia and the pathophysiology of language by the neurobiologist Christfried Jakob (1866–1956) of Buenos Aires, and to place them in a modern perspective. The morphofunctional basis of human language and its pathology occupied Jakob’s mind over three decades. His synthetic conclusions were based on the neuropathological examination of dozens of aphasic cases from the Hospital de Las Mercedes and the National Women’s Psychiatric Hospital between 1906 and 1936. Special mention is made of the role of the cerebellum, the thalamus, and their connections with the cerebral cortex, and the language network. Current research and imaging studies support and elaborate that which Jacob presented so many years ago; many of his analyses and ideas are informative and remain relevant today.

查看原文本刊更多论文

Christfried Jakob（1866-1956）关于语言和失语症的神经生物学和病理生理学概念：两种交流的英译[1901932]和现代视角。

本文的目的是在英文翻译中保留布宜诺斯艾利斯神经生物学家Christfried Jakob（1866-1956）关于失语症和语言病理生理学的两次历史交流，并将其置于现代视野中。人类语言的形态功能基础及其病理学占据了雅各布三十多年的思想。他的综合结论是基于1906年至1936年间对拉斯梅塞德斯医院和国家妇女精神病医院数十例失语症患者的神经病理学检查得出的。特别提到了小脑、丘脑的作用，以及它们与大脑皮层和语言网络的联系。目前的研究和成像研究支持并阐述了雅各布多年前提出的观点；他的许多分析和观点都是翔实的，至今仍具有现实意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of chemical neuroanatomy 医学-神经科学

CiteScore

4.50

自引率

3.60%

发文量

审稿时长

62 days

期刊介绍： The Journal of Chemical Neuroanatomy publishes scientific reports relating the functional and biochemical aspects of the nervous system with its microanatomical organization. The scope of the journal concentrates on reports which combine microanatomical, biochemical, pharmacological and behavioural approaches. Papers should offer original data correlating the morphology of the nervous system (the brain and spinal cord in particular) with its biochemistry. The Journal of Chemical Neuroanatomy is particularly interested in publishing important studies performed with up-to-date methodology utilizing sensitive chemical microassays, hybridoma technology, immunocytochemistry, in situ hybridization and receptor radioautography, to name a few examples. The Journal of Chemical Neuroanatomy is the natural vehicle for integrated studies utilizing these approaches. The articles will be selected by the editorial board and invited reviewers on the basis of their excellence and potential contribution to this field of neurosciences. Both in vivo and in vitro integrated studies in chemical neuroanatomy are appropriate subjects of interest to the journal. These studies should relate only to vertebrate species with particular emphasis on the mammalian and primate nervous systems.