Trends, challenges, and success factors in pharmaceutical portfolio management: Cognitive biases in decision-making and their mitigating measures

IF 6.5 2区 医学 Q1 PHARMACOLOGY & PHARMACY
Linn Bieske , Maximillian Zinner , Florian Dahlhausen , Hubert Trübel
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引用次数: 1

Abstract

Effective portfolio management is crucial for innovation and sustaining revenue in pharmaceutical companies. This article holistically reviews trends, challenges, and approaches to pharmaceutical portfolio management and focuses, in particular, on cognitive biases in portfolio decision-making. Portfolio managers strongly rely on external innovation and face increasing competitive pressure and portfolio complexity. The ability to address biases and make robust decisions remains a challenge. Portfolio management practitioners most commonly face confirmation bias, champion bias, or misaligned incentives, which they seek to mitigate through expert input, team diversity, and rewarding truth-seeking. Ultimately, highest-quality portfolio management decision-making could be enabled by three factors: high-quality data, structured review processes, and comprehensive mitigating measures against biases in decision-making.

药品投资组合管理的趋势、挑战和成功因素:决策中的认知偏差及其缓解措施
有效的投资组合管理对制药公司的创新和维持收入至关重要。本文全面地回顾了制药投资组合管理的趋势、挑战和方法,并特别关注投资组合决策中的认知偏差。投资组合经理强烈地依赖于外部创新,并且面临着日益增长的竞争压力和投资组合的复杂性。解决偏见和做出稳健决策的能力仍然是一个挑战。投资组合管理实践者最常见的是面对确认偏差、冠军偏差,或者不一致的激励,他们寻求通过专家输入、团队多样性和奖励寻求真相来减轻这些偏差。最终,最高质量的投资组合管理决策可以通过三个因素来实现:高质量的数据、结构化的审查过程,以及针对决策偏差的综合缓解措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Drug Discovery Today
Drug Discovery Today 医学-药学
CiteScore
14.80
自引率
2.70%
发文量
293
审稿时长
6 months
期刊介绍: Drug Discovery Today delivers informed and highly current reviews for the discovery community. The magazine addresses not only the rapid scientific developments in drug discovery associated technologies but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed. Features include comment by international experts, news and analysis of important developments, reviews of key scientific and strategic issues, overviews of recent progress in specific therapeutic areas and conference reports.
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