Deciphering the cancer genome and epigenome

IF 72.5 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2023-06-07 DOI:10.1038/s41568-023-00590-6

Isabel Esain-Garcia

引用次数: 0

Abstract

In this Tools of the Trade article, Isabel Esain-Garcia describes the development and use of a 6-letter whole-genome sequencing technology, which enables the simultaneous acquisition of genetic and epigenetic information from human genomic and cell-free DNA, which has implications for improving our biological understanding of cancer as well as cancer diagnosis and early intervention.

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解读癌症基因组和表观基因组。

在这篇 "贸易工具"（Tools of the Trade）文章中，伊莎贝尔-埃塞因-加西亚（Isabel Esain-Garcia）介绍了6字母全基因组测序技术的开发和使用情况，该技术可同时从人类基因组和无细胞DNA中获取遗传和表观遗传信息，对提高我们对癌症的生物学认识以及癌症诊断和早期干预具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.