The Effects of Three Different Low-molecular-weight Heparins on Blood Loss After Intramedullary Nailing of Trochanteric Fractures.

Mirza Sivro, Djemil Omerovic, Faruk Lazovic, Adnan Papovic
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Abstract

Background: The three most commonly used low-molecular-weight heparins (LMWH) in Bosnia and Herzegovina for thromboprophylaxis in patients with hip fracture are reviparin, dalteparin and enoxaparin.

Objective: The purpose of this study was to compare the effects of reviparin, dalteparin and enoxaparin on intraoperative blood loss in patients with trochanteric fracture treated with intramedullary nailing.

Methods: This retrospective multicenter study included 100 patients with trochanteric fracture who were divided into three groups according to the low-molecular-weight heparin administered. In all cases, a short third generation Gamma-nail was used for osteosynthesis. Complete blood count and number of red blood cell transfusions (RBC) were evaluated. Results: The mean value of postoperative hemoglobin level was lower in the enoxaparin group compared to the reviparin group, with significant difference (p=0.001; 95% CI: 4.1-18.87). Patients in the dalteparin group received more RBC transfusions compared to the reviparin and enoxaparin group (p=0.048).

Conclusion: The use of enoxaparin and dalteparin in hip fracture patients can result in lower postoperative haemoglobin levels and more RBC transfusions compared to reviparin.

Abstract Image

Abstract Image

Abstract Image

三种不同低分子肝素对股骨粗隆间骨折髓内钉治疗后失血量的影响。
背景:在波斯尼亚和黑塞哥维那,用于预防髋部骨折患者血栓形成的三种最常用的低分子肝素(LMWH)是瑞肝素、达肝素和依诺肝素。目的:本研究的目的是比较雷肝素、达肝素和依诺肝素对髓内钉治疗大转子骨折患者术中失血的影响。方法:这项回顾性多中心研究纳入了100名大转子骨折患者,他们根据服用的低分子肝素分为三组。在所有病例中,均使用第三代伽玛钉进行骨合成。评估全血细胞计数和红细胞输注次数。结果:依诺肝素组术后血红蛋白水平的平均值低于瑞肝素组,有显著差异(p=0.001;95%可信区间:4.1-18.87)。与依诺肝素和依诺肝素组相比,达肝素组患者接受了更多的红细胞输注(p=0.048)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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