The inflammation process of gout arthritis and its treatment.

IF 1.4 Q3 Pharmacology, Toxicology and Pharmaceutics
Nita Parisa, Muhammad Totong Kamaluddin, Masagus Irsan Saleh, Ernawati Sinaga
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引用次数: 0

Abstract

Gout arthritis is an inflammatory condition that occurs suddenly in joints affected by high uric acid levels (hyperuricemia). The uric acid levels in this disease fluctuate throughout its various phases, resulting in frequent or recurrent attacks. This study aims to review some aspects of gout arthritis, such as its pathophysiology, treatment goals, and adverse drug reactions. This study employs review literature using articles published between 2017 and 2022 as the research methodology. Furthermore, articles under 2017 are used as references if they are relevant to the study's subject matter. The findings showed the importance of the pathogenesis of inflammation in the treatment of gout arthritis. It is also recommended to use anti-inflammatories such as colchicine and uric acid-lowering medications starting at a specific time to prevent unintended risks. Hence, pharmacotherapy management's adverse effects include nausea, vomiting, myalgia, neuropathy, and stomach pain.

Abstract Image

Abstract Image

痛风性关节炎的炎症过程及其治疗。
痛风性关节炎是一种突然发生在受高尿酸水平(高尿酸血症)影响的关节中的炎症性疾病。这种疾病的尿酸水平在各个阶段都会波动,导致频繁或反复发作。本研究旨在综述痛风性关节炎的一些方面,如其病理生理学、治疗目标和药物不良反应。本研究采用了2017年至2022年间发表的综述文献作为研究方法。此外,如果2017年以下的文章与研究主题相关,则可作为参考。研究结果显示了炎症发病机制在痛风性关节炎治疗中的重要性。还建议在特定时间开始使用秋水仙碱和降尿酸药物等抗炎药,以防止意外风险。因此,药物治疗的不良反应包括恶心、呕吐、肌痛、神经病变和胃痛。
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来源期刊
CiteScore
2.00
自引率
7.10%
发文量
44
审稿时长
20 weeks
期刊介绍: Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is an Official Publication of Society of Pharmaceutical Education & Research™. It is an international journal published Quarterly. Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is available in online and print version. It is a peer reviewed journal aiming to communicate high quality original research work, reviews, short communications, case report, Ethics Forum, Education Forum and Letter to editor that contribute significantly to further the scientific knowledge related to the field of Pharmacy i.e. Pharmaceutics, Pharmacology, Pharmacognosy, Pharmaceutical Chemistry. Articles with timely interest and newer research concepts will be given more preference.
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