Effect of valve leaflet surface patterning on valve hydrodynamic performance.

IF 1.4 4区医学 Q4 ENGINEERING, BIOMEDICAL

International Journal of Artificial Organs Pub Date : 2023-10-01 Epub Date: 2023-09-12 DOI:10.1177/03913988231192118

Aili Wang, Yumiao Wang, Wanbing Liu, Li Liu, Jianye Zhou

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引用次数: 0

Abstract

Objective: We aimed to elucidate the effects of the micro-structure of the pyrolytic carbon for artificial heart valves on its hydrodynamic performance.

Methods: Bileaflet mechanical valves of GKS 23 and 29 A were randomly selected. According to ISO5840, mean transvalvular pressure (MPG), regurgitation fraction (RF), and effective orifice area (EOA) of valve were assessed. Then, parallel-groove pattern was constructed by laser etching on leaflet surface, and the valves were subjected again to the same test.

Results: Compared with before patterning at 2, 3.5, 5, and 7 L/min, the MPG of the valves in two specifications were higher, the EOA was larger in 23 A, but smaller in 29 A, and the RF was contrary to EOA. At 5 L/min, the RF in both specifications was lower after etching at 45 bpm. At 70 bpm however, the RF in 23 A decreased, in 29 A increased.

Conclusion: The parallel-groove pattern on leaflet surface affected the hemodynamic performance of the valve prostheses.

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阀叶表面图案对阀液动力性能的影响。

目的：阐明人工心脏瓣膜用热解炭的微观结构对其流体力学性能的影响。方法：采用GKS 23和29的双瓣机械瓣膜 A是随机选择的。根据ISO5840，评估瓣膜的平均跨瓣压（MPG）、反流分数（RF）和有效瓣口面积（EOA）。然后，通过激光蚀刻在瓣叶表面上构建平行凹槽图案，并再次对瓣膜进行相同的测试。结果：与2、3.5、5和7图案化前相比 L/min，两种规格的阀门的MPG更高，23种规格的EOA更大 A、但在29 A、 RF与EOA相反。在5 L/分钟，在45蚀刻后，两种规格的RF都较低 bpm。70岁 bpm然而，23中的RF A下降，在29 A增加了。结论：瓣叶表面的平行凹槽模式影响了人工瓣膜的血流动力学性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Artificial Organs 医学-工程：生物医学

CiteScore

3.40

自引率

5.90%

发文量

审稿时长

3 months

期刊介绍： The International Journal of Artificial Organs (IJAO) publishes peer-reviewed research and clinical, experimental and theoretical, contributions to the field of artificial, bioartificial and tissue-engineered organs. The mission of the IJAO is to foster the development and optimization of artificial, bioartificial and tissue-engineered organs, for implantation or use in procedures, to treat functional deficits of all human tissues and organs.