Effect of valve leaflet surface patterning on valve hydrodynamic performance.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-10-01 Epub Date: 2023-09-12 DOI:10.1177/03913988231192118

Aili Wang, Yumiao Wang, Wanbing Liu, Li Liu, Jianye Zhou

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引用次数: 0

Abstract

Objective: We aimed to elucidate the effects of the micro-structure of the pyrolytic carbon for artificial heart valves on its hydrodynamic performance.

Methods: Bileaflet mechanical valves of GKS 23 and 29 A were randomly selected. According to ISO5840, mean transvalvular pressure (MPG), regurgitation fraction (RF), and effective orifice area (EOA) of valve were assessed. Then, parallel-groove pattern was constructed by laser etching on leaflet surface, and the valves were subjected again to the same test.

Results: Compared with before patterning at 2, 3.5, 5, and 7 L/min, the MPG of the valves in two specifications were higher, the EOA was larger in 23 A, but smaller in 29 A, and the RF was contrary to EOA. At 5 L/min, the RF in both specifications was lower after etching at 45 bpm. At 70 bpm however, the RF in 23 A decreased, in 29 A increased.

Conclusion: The parallel-groove pattern on leaflet surface affected the hemodynamic performance of the valve prostheses.

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阀叶表面图案对阀液动力性能的影响。

目的：阐明人工心脏瓣膜用热解炭的微观结构对其流体力学性能的影响。方法：采用GKS 23和29的双瓣机械瓣膜 A是随机选择的。根据ISO5840，评估瓣膜的平均跨瓣压（MPG）、反流分数（RF）和有效瓣口面积（EOA）。然后，通过激光蚀刻在瓣叶表面上构建平行凹槽图案，并再次对瓣膜进行相同的测试。结果：与2、3.5、5和7图案化前相比 L/min，两种规格的阀门的MPG更高，23种规格的EOA更大 A、但在29 A、 RF与EOA相反。在5 L/分钟，在45蚀刻后，两种规格的RF都较低 bpm。70岁 bpm然而，23中的RF A下降，在29 A增加了。结论：瓣叶表面的平行凹槽模式影响了人工瓣膜的血流动力学性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.