The burden of major depressive disorder in the Middle East and North Africa region, 1990-2019.

IF 3.8 4区医学 Q1 Medicine

Acta Neuropsychiatrica Pub Date : 2024-06-01 Epub Date: 2023-09-11 DOI:10.1017/neu.2023.42

Saeid Safiri, Seyed Ehsan Mousavi, Seyed Aria Nejadghaderi, Maryam Noori, Mark J M Sullman, Ali-Asghar Kolahi, Reza Shekarriz-Foumani

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引用次数: 0

Abstract

Background: Major depressive disorder (MDD) is one of the leading causes of disability. We aimed to report the MDD-attributable prevalence, incidence and years lived with disability (YLDs) in the Middle East and North Africa (MENA) region from 1990 to 2019 by age, sex and socio-demographic index (SDI).

Methods: Publicly available data on the burden of MDD were retrieved from the Global Burden of Disease (GBD) study 2019 for the 21 countries in MENA. The counts and age-standardised rates (per 100,000) were presented, along with their corresponding 95% uncertainty intervals.

Results: In 2019, MDD had an age-standardised point prevalence of 3322.1 and an incidence rate of 4921.7 per 100,000 population in MENA. Furthermore, there were 4.1 million YLDs in 2019. However, there were no substantial changes in the MDD burden over the period 1990-2019. In 2019, Palestine had the highest burden of MDD. The highest prevalence, incidence and YLDs attributable to MDD were found in the 35-39 age group. In 2019, the YLD rate in MENA was higher than the global rate for almost all age groups. Furthermore, there was a broadly negative association between the YLD rate and SDI.

Conclusion: The study highlights the need to prevent the disorder using a multidisciplinary approach and for the provision of cost-effective treatments for those affected, in order to increase their quality of life.

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1990年至2019年中东和北非地区重度抑郁症的负担。

背景：重度抑郁障碍（MDD）是导致残疾的主要原因之一。我们旨在通过年龄、性别和社会形态指数（SDI）报告1990年至2019年中东和北非（MENA）地区MDD可归因的患病率、发病率和残疾寿命（YLD）。方法：从2019年全球疾病负担（GBD）研究中检索21个中东和北非国家MDD负担的公开可用数据。给出了计数和年龄标准化率（每100000人），以及相应的95%不确定性区间。结果：2019年，中东和北非地区MDD的年龄标准化点患病率为3322.1，发病率为每100000人4921.7。此外，2019年有410万YLD。然而，在1990-2019年期间，MDD负担没有发生实质性变化。2019年，巴勒斯坦的MDD负担最高。可归因于MDD的最高患病率、发病率和YLD发生在35-39岁年龄组。2019年，中东和北非地区几乎所有年龄组的YLD发病率都高于全球。此外，YLD发病率和SDI之间存在广泛的负相关。结论：该研究强调了使用多学科方法预防该疾病的必要性，并为受影响的人提供具有成本效益的治疗，以提高他们的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Neuropsychiatrica 医学-精神病学

CiteScore

8.50

自引率

5.30%

发文量

审稿时长

6-12 weeks

期刊介绍： Acta Neuropsychiatrica is an international journal focussing on translational neuropsychiatry. It publishes high-quality original research papers and reviews. The Journal''s scope specifically highlights the pathway from discovery to clinical applications, healthcare and global health that can be viewed broadly as the spectrum of work that marks the pathway from discovery to global health.

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