Barriers and facilitators related to COVID-19 vaccine acceptance and uptake among people living with HIV.

IF 4.5 3区 医学 Q2 IMMUNOLOGY
Kristen D Krause, Rafael E Pérez-Figueroa, Perry N Halkitis
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引用次数: 0

Abstract

Purpose of review: This review reports on the myriad barriers and facilitators related to COVID-19 vaccine hesitancy and factors contribution to uptake among people living with HIV (PLWH) globally published over the past year (2021-2022).

Recent findings: Across the literature, participants indicated concerns about the safety, efficacy and overall rapid development of the COVID-19 vaccine as a reason for delaying or not being vaccinated. Medical mistrust and perceptions about the risk of COVID-19 immune response and severity also played a role in COVID-19 vaccine hesitancy among PLWH. Almost every study examined different sociodemographic characteristics associated with COVID-19 vaccination acceptance and uptake, and although strong themes emerged around race/ethnicity, sex and educational attainment, the results were mixed across other characteristics, including age. Some studies also examined medical factors specifically related to PLWH including CD4 + cell count and adherence to antiretroviral therapy.

Summary: The findings highlight individual, structural and social differences in COVID-19 vaccine acceptance and uptake among PLWH, which are varied throughout the world. We call on researchers and interventionists to not just consider the role of medical mistrust and disinformation, but also how emotional, financial and political vulnerability plays into making decisions around COVID-19 vaccine uptake and overall healthcare.

与艾滋病毒感染者接受和使用COVID-19疫苗有关的障碍和促进因素。
综述目的:本综述报告了过去一年(2021-2022年)全球发表的与COVID-19疫苗犹豫相关的无数障碍和促进因素,以及导致艾滋病毒感染者(PLWH)接种疫苗的因素。最近的发现:在所有文献中,参与者都表示对COVID-19疫苗的安全性、有效性和整体快速发展的担忧,这是推迟或不接种疫苗的原因。医疗不信任和对COVID-19免疫反应风险和严重程度的看法也在PLWH中对COVID-19疫苗犹豫不决中发挥了作用。几乎每一项研究都调查了与COVID-19疫苗接受和吸收相关的不同社会人口特征,尽管围绕种族/民族、性别和受教育程度出现了强烈的主题,但包括年龄在内的其他特征的结果却参差不齐。一些研究还检查了与PLWH特别相关的医学因素,包括CD4 +细胞计数和抗逆转录病毒治疗的依从性。总结:研究结果突出了PLWH在COVID-19疫苗接受和摄取方面的个体、结构和社会差异,这些差异在世界各地各不相同。我们呼吁研究人员和干预主义者不仅要考虑医疗不信任和虚假信息的作用,还要考虑情绪、经济和政治脆弱性如何影响围绕COVID-19疫苗接种和整体医疗保健做出决策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Opinion in HIV and AIDS
Current Opinion in HIV and AIDS IMMUNOLOGY-INFECTIOUS DISEASES
CiteScore
7.40
自引率
7.30%
发文量
115
审稿时长
6-12 weeks
期刊介绍: Published bimonthly and offering a unique and wide ranging perspective on the key developments in the field, each issue of Current Opinion in HIV and AIDS features hand-picked review articles from our team of expert editors. With six disciplines published across the year – including HIV and ageing, a HIV vaccine, and epidemiology – every issue also contains annotated reference detailing the merits of the most important papers.
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