Evaluation of hypertension control among hemodialysis patients in Pakistan: a prospective follow-up study.

IF 1.2 4区医学 Q4 PERIPHERAL VASCULAR DISEASE

Blood Pressure Monitoring Pub Date : 2023-10-01 Epub Date: 2023-07-06 DOI:10.1097/MBP.0000000000000656

Kiran Hameed, Sampath Chinnam, Khanzada Sheraz Khan, Saima Mushtaq, Nafees Ahmad, Ammar Ali Saleh Jaber, Zeeshan Anwar, Inayat Ur-Rehman, Amjad Khan

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Abstract

Background: Hypertension is highly prevalent and uncontrolled among hemodialysis patients. In Pakistan published data does not provide enough information about the management and factors associated with uncontrolled hypertension in hemodialysis patients.

Objective: This study was conducted to evaluate the factors influencing the pharmacotherapeutic management and control of hypertension in hemodialysis patients.

Methods: A prospective follow-up study was conducted on hemodialysis patients who were enrolled at study sites between 1 June 2020 and 31 December 2020. The predialysis blood pressure (BP) readings were recorded as mean SBP and DBP at baseline and for each of 6 months. Multivariate analyses were applied to analyze the factors associated with uncontrolled hypertension in hemodialysis patients.

Results: The average predialysis BP (SBP and DBP) of study participants at baseline visit was 158.41 and 87.22 mmHg respectively. After 6 months the study participants have 150.27 mmHg and 80.03 mmHg average predialysis SBP and DBP respectively. Only 28.1% of hemodialysis patients were on target BP after 6 months. Results of multivariate analysis have shown that the use of beta-blockers and calcium channel blockers (CCBs) were significantly associated with hypertension control at baseline [odds ratio (OR) = 1.432, P value = 0.034] (OR = 1.499, P value = 0.045) and at after 6 months (OR = 2.824, P value = 0.015) (OR = 1.883, P value = 0.032).

Conclusion: This study revealed that among the antihypertensive drugs, CCBs and beta-blockers provided better management in controlling hypertension among hemodialysis patients.

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巴基斯坦血液透析患者高血压控制的评价:一项前瞻性随访研究。

背景：高血压在血液透析患者中非常普遍且不受控制。在巴基斯坦，公布的数据没有提供足够的信息，说明血液透析患者高血压失控的管理和相关因素。目的：评价影响血液透析患者高血压药物治疗管理和控制的因素。方法：对2020年6月1日至2020年12月31日期间在研究地点登记的血液透析患者进行前瞻性随访研究。分析前血压（BP）读数记录为基线时的平均SBP和DBP，6 月。采用多因素分析法分析血液透析患者高血压失控的相关因素。结果：研究参与者在基线访视时的平均分析前血压（SBP和DBP）分别为158.41和87.22 mmHg。6之后研究参与者有150.27个月 mmHg和80.03 mmHg平均分析前收缩压和舒张压。只有28.1%的血液透析患者在6年后达到目标血压月。多变量分析结果表明，β受体阻滞剂和钙通道阻滞剂（CCBs）的使用与基线时的高血压控制显著相关[比值比（OR） = 1.432，P值 = 0.034]（或 = 1.499，P值 = 0.045）和在6之后月（或 = 2.824，P值 = 0.015）（或 = 1.883，P值 = 0.032）。结论：本研究表明，在抗高血压药物中，CCBs和β受体阻滞剂在控制血液透析患者高血压方面提供了更好的管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Blood Pressure Monitoring 医学-外周血管病

CiteScore

2.00

自引率

7.70%

发文量

110

审稿时长

>12 weeks

期刊介绍： Blood Pressure Monitoring is devoted to original research in blood pressure measurement and blood pressure variability. It includes device technology, analytical methodology of blood pressure over time and its variability, clinical trials - including, but not limited to, pharmacology - involving blood pressure monitoring, blood pressure reactivity, patient evaluation, and outcomes and effectiveness research. This innovative journal contains papers dealing with all aspects of manual, automated, and ambulatory monitoring. Basic and clinical science papers are considered although the emphasis is on clinical medicine. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.