Efficacy and Safety of Iris-Claw Intraocular Lens in Pediatric Ectopia Lentis: A Literature Review.

IF 1.2 Q3 OPHTHALMOLOGY

Journal of Current Ophthalmology Pub Date : 2023-01-01 DOI:10.4103/joco.joco_249_22

Dian Estu Yulia, Diajeng Ayesha Soeharto

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Abstract

Purpose: To review current evidence regarding the use of iris-claw intraocular lens (IOL) in terms of its efficacy and safety in the population of pediatric ectopia lentis. Methods: A comprehensive literature search of six electronic databases (PubMed-NCBI, Medline-OVID, Embase, Cochrane, Scopus, and Wiley) and secondary search through reference lists was conducted using keywords selected a priori. All primary studies on the use of iris-claw in pediatric ectopia lentis that evaluated visual acuity (VA), complications, and endothelial cell density (ECD) were included and critically appraised using the Newcastle–Ottawa Scale. Results: Ten studies were eligible for inclusion with an overall sample size of 168 eyes of children with ectopia lentis, and the majority of studies evaluated anterior iris-claw IOL. All studies reported improvement in postoperative VA. The most commonly reported complication across studies was IOL decentration. All studies reported decreasing ECD, and this was observed in both anterior and retropupillary iris-claw IOL. Conclusion: Current evidence shows that iris-claw IOL is effective in terms of improving VA in pediatric ectopia lentis. Due to the lack of long-term evidence of its safety in children, one must remain cautious regarding potential endothelial cell loss. Further high-quality, interventional, long-term studies are needed.

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虹膜-爪形人工晶状体治疗儿童晶状体异位的疗效和安全性:文献综述。

目的:回顾目前关于虹膜爪形人工晶状体(IOL)在儿童晶状体异位人群中的有效性和安全性的证据。方法:对PubMed-NCBI、Medline-OVID、Embase、Cochrane、Scopus、Wiley等6个电子数据库进行综合文献检索，并采用先验选择的关键词通过参考文献列表进行二次检索。所有使用虹膜钳法治疗儿童异位晶状体的初步研究都纳入了评估视力(VA)、并发症和内皮细胞密度(ECD)的研究，并使用纽卡斯尔-渥太华量表进行了严格评价。结果:10项研究符合纳入标准，总样本量为168只眼的儿童晶状体异位，大多数研究评估前虹膜-爪形人工晶状体。所有研究都报告了术后VA的改善。所有研究中最常见的并发症是IOL脱位。所有的研究都报告了ECD降低，这在瞳孔前和瞳孔后虹膜-爪式人工晶状体中都观察到了。结论:目前的证据表明，虹膜-爪形人工晶状体植入术对改善儿童异位晶状体的视功能是有效的。由于缺乏长期证据证明其在儿童中的安全性，因此必须对潜在的内皮细胞损失保持谨慎。需要进一步的高质量、干预性、长期研究。

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来源期刊

Journal of Current Ophthalmology OPHTHALMOLOGY-

CiteScore

2.50

自引率

6.70%

发文量

审稿时长

8 weeks

期刊介绍： Peer Review under the responsibility of Iranian Society of Ophthalmology Journal of Current Ophthalmology, the official publication of the Iranian Society of Ophthalmology, is a peer-reviewed, open-access, scientific journal that welcomes high quality original articles related to vision science and all fields of ophthalmology. Journal of Current Ophthalmology is the continuum of Iranian Journal of Ophthalmology published since 1969.