Bionics investigation of blood 25-hydroxyvitamin D in the interpretable biomechanics diagnosis of childhood anemia.

IF 1.4 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Lechi Zhang, Aijie Huang, Jingye Cai, Jiangting Hou, Hongyan Deng, Chenxiao Liu
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引用次数: 1

Abstract

Vitamin D deficiency (VDD) causes a wide range of health problems, including anemia in infants. If not treated promptly, it may create serious issues for infants with long-term impacts. Therefore, a satisfactory solution to this problem is required. This investigation was to explore the correlation between the blood 25-hydroxyvitamin D (25(OH)D) levels and childhood anemia. In this investigation, a cross-sectional examination was performed on 2,942 babies ranging in age from 2 to 36 months and classified into three cohorts: VDD (Vitamin D deficiency), VDI (Vitamin D insufficiency), and VDS (Vitamin D sufficiency). Multiple-variables and multinomially-related logistic regressions for examining the anemia status-vitamin D (Vit-D) relationship of the baseline as the interpretable visual quality models were examined. The median serum 25(OH)D level in 2,942 infants was 24.72±4.26 ng/l, with 661 cases (22.5%) of VDD and 1710 cases of deficiency (58.1%), and a noticeable seasonal variation (p<0.05). Anemia was present in 28.5% of the VDD group compared with 3.3% in vit-D sufficient infants (p<0.0001). Lower levels of 25(OH)D were found to be associated with an increased risk of anemia in a multiple-variable regression analysis. In healthy children, low 25(OH)D levels were associated with increased risk of anemia. Biologically inspired, primary care physicians should assess Vit-D levels and place a greater emphasis on adequate supplementation for deficiency prevention.

血液25-羟基维生素D在儿童贫血可解释生物力学诊断中的仿生研究。
维生素D缺乏症(VDD)会导致一系列健康问题,包括婴儿贫血。如果不及时治疗,可能会给婴儿带来长期影响的严重问题。因此,这个问题需要一个令人满意的解决方案。本研究旨在探讨血液25-羟基维生素D(25(OH)D)水平与儿童贫血之间的相关性。在这项调查中,对2942名年龄从2个月到36个月的婴儿进行了横断面检查,并将其分为三组:VDD(维生素D缺乏)、VDI(维生素D不足)和VDS(维生素D充足)。检查了作为可解释视觉质量模型的基线的贫血状态-维生素D(Vit-D)关系的多变量和多指标相关逻辑回归。2942名婴儿的血清25(OH)D水平中位数为24.72±4.26ng/l,其中661例(22.5%)为VDD,1710例为缺乏型(58.1%),季节变化显著(p
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来源期刊
Acta biochimica Polonica
Acta biochimica Polonica 生物-生化与分子生物学
CiteScore
2.40
自引率
0.00%
发文量
99
审稿时长
4-8 weeks
期刊介绍: Acta Biochimica Polonica is a journal covering enzymology and metabolism, membranes and bioenergetics, gene structure and expression, protein, nucleic acid and carbohydrate structure and metabolism.
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