Monitoring the positive conversion of anti-erythrocyte antibodies in blood transfusion donor horses.

Q3 Veterinary
Hironaga Kakoi, Mio Kikuchi, Taichiro Ishige, Yuko Hirosawa, Shoko Tanaka, Shun-Ichi Nagata
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引用次数: 0

Abstract

To confirm the positive conversion of antibodies against erythrocyte antigens in horses, possible blood transfusion donor horses selected from draft horse populations were periodically monitored with an indirect antiglobulin (Coombs) test for approximately 3 years. In this study, 19 horses (16 females and 3 males) were investigated, and five mares showed alloantibodies during the monitoring period. Four mares were typically pregnant when positive conversion was detected, whereas no particular cause of conversion could be observed for one mare based on its clinical records. In the analyzed horses, most positive conversions were possibly due to pregnancy, as conversion occurred more often during this period than after parturition. Pregnancy is considered a key event for positive conversion. Additionally, in cases in which unknown causative sensitization is confirmed, continuous monitoring with a test to detect antibodies should be performed, even if the possible donor is selected and maintained.

输血供马抗红细胞抗体阳性转化的监测。
为了确认马体内抗红细胞抗原抗体的阳性转化,从役马群中选择可能输血的供体马,定期进行间接抗球蛋白(Coombs)检测,监测时间约为3年。本研究对19匹马(母马16匹,公马3匹)进行了调查,其中5匹马在监测期间出现同种异体抗体。当检测到阳性转化时,四匹母马通常怀孕,而根据其临床记录,一匹母马没有观察到特定的转化原因。在分析的马中,大多数积极的转换可能是由于怀孕,因为转换在此期间比分娩后更频繁。怀孕被认为是积极转变的关键事件。此外,在确认未知致敏的病例中,即使选择并维持可能的供体,也应通过检测抗体的试验进行持续监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Equine Science
Journal of Equine Science Veterinary-Equine
CiteScore
1.60
自引率
0.00%
发文量
9
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