The Influence of Implant Design Features on the Bone Healing Pathway: An Experimental Study in Sheep.

IF 1.3 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

International Journal of Periodontics & Restorative Dentistry Pub Date : 2023-05-01 DOI:10.11607/prd.5438

Edmara T P Bergamo, Paula G F P de Oliveira, Ryo Jimbo, Rodrigo Neiva, Luiz F Gil, Nick Tovar, Lukasz Witek, Estevam A Bonfante, Paulo G Coelho

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引用次数: 1

Abstract

This study evaluated how implant design features influence osseointegration. Two implant macrogeometries and surface treatments were evaluated: (1) progressive buttress threads with an SLActive surface (SLActive/BL), and (2) inner and outer trapezoidal threads with a nanohydroxyapatite coating over a dual acid-etched surface (Nano/U). Implants were placed in the right ilium of 12 sheep, and histologic and -metric analyses were conducted after 12 weeks. Percentages of bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO) within the threads were quantified. Histologically, the SLActive/BL group showed greater and more intimate BIC than the Nano/U group. In contrast, Nano/U group depicted woven bone formation within the healing chambers, between the osteotomy wall and implant threads, and bone remodeling was evident at the outer thread tip. Significantly higher BAFO was seen in the Nano/U group than the SLActive/BL group at 12 weeks (P < .042). Different implant design features influenced the osseointegration pathway, supporting further investigations to describe the differences and clinical performance.

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种植体设计特征对羊骨愈合途径影响的实验研究。

本研究评估种植体设计特征对骨整合的影响。评估了两种种植体的宏观几何形状和表面处理:(1)SLActive表面的渐进式支撑螺纹(SLActive/BL)和(2)在双酸蚀刻表面上涂有纳米羟基磷灰石涂层的内外梯形螺纹(Nano/U)。将植入物置于12只羊的右髂骨，12周后进行组织学和计量学分析。量化骨与种植体接触百分率(BIC)和骨面积百分率(BAFO)。组织学上，SLActive/BL组比Nano/U组表现出更大、更亲密的BIC。相比之下，纳米/U组在愈合腔内，在切骨壁和种植体螺纹之间描绘了编织骨形成，骨重塑在外螺纹尖端明显。12周时，Nano/U组BAFO明显高于SLActive/BL组(P < 0.042)。不同的种植体设计特征会影响骨整合途径，支持进一步的研究来描述差异和临床表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Periodontics & Restorative Dentistry 医学-牙科与口腔外科

CiteScore

2.90

自引率

6.20%

发文量

113

审稿时长

6-12 weeks

期刊介绍： The International Journal of Periodontics & Restorative Dentistry will publish manuscripts concerned with all aspects of clinical periodontology, restorative dentistry, and implantology. This includes pertinent research as well as clinical methodology (their interdependence and relationship should be addressed where applicable); proceedings of relevant symposia or conferences; and quality review papers. Original manuscripts are considered for publication on the condition that they have not been published or submitted for publication elsewhere.