Efficacy of Laser in Hair Removal: A Network Meta-analysis.

IF 1.2 4区 医学 Q3 DERMATOLOGY
Yu-Chien Kao, Dai-Zhu Lin, Yi-No Kang, Cheng-Jen Chang, Wen-Kuan Chiu, Chiehfeng Chen
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引用次数: 0

Abstract

Background: Laser hair removal is an increasingly prevalent trend of cosmetic procedures. The purpose of this study was to assess the effectiveness of hair reduction among several types of laser interventions.

Methods: The selected studies searched in PubMed and EMBASE were assessed for quality of evidence, and extracted data on absolute hair count and hair reduction rate. Qualitative data were synthesized using standardized mean difference (SMD) in frequentist network meta-analysis because various measurement units were used among selected studies. Inconsistency and small study effects were examined by design-by-treatment interaction model and comparison-adjusted funnel plot.

Results: A total of 13 randomized controlled trials (RCTs) (n = 652) were contributed to network meta-analysis. Pooled results revealed that diode laser showed significantly lower absolute hair count within three-month (SMD = -13.21, 95% confidence interval [CI]: -22.25 to -4.17) and around six months follow-up (SMD = -11.01, 95% CI: -18.24 to -3.77) as compared with those in control group, but no significant difference among laser interventions. All side effects observed were transient without leaving any permanent scars.

Conclusion: Eliminating unwanted hair with lasers or intense pulsed light is safe and effective; however, which type of intervention is more beneficial in the long-term process should be studied with a longer follow-up time.

激光脱毛的疗效:网络荟萃分析。
背景:激光脱毛是一种日益流行的美容手术。本研究的目的是评估几种类型的激光干预脱发的有效性。方法:选取在PubMed和EMBASE中检索的研究进行证据质量评估,提取绝对毛发数和毛发减少率数据。由于所选研究使用了不同的测量单位,因此定性数据采用频率网络元分析中的标准化平均差(SMD)进行综合。通过设计-处理相互作用模型和比较调整漏斗图检验不一致性和小研究效应。结果:网络荟萃分析共纳入13项随机对照试验(rct) (n = 652)。综合结果显示,与对照组相比,二极管激光治疗组3个月内(SMD = -13.21, 95%可信区间[CI]: -22.25 ~ -4.17)和随访6个月左右(SMD = -11.01, 95% CI: -18.24 ~ -3.77)的绝对毛数明显降低,但激光治疗组间差异无统计学意义。观察到的所有副作用都是短暂的,没有留下任何永久的疤痕。结论:激光或强脉冲光去除多余毛发安全有效;然而,哪种干预方式在长期过程中更有益,需要更长的随访时间进行研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.50
自引率
0.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: A unique journal that focuses on the application of cosmetic laser and light therapies on the skin. The Journal of Cosmetic & Laser Therapy provides a forum for stimulating and up-to-date studies demonstrating the wide range of therapeutic options for clinicians and surgeons involved in cosmetic and dermatological treatment. The journal is aimed at dermatologists, cosmetic surgeons, plastic and facial plastic surgeons, oculoplastic surgeons and all those interested in the rapidly expanding field of cosmetic and laser therapy. Features include: -Cosmetic surgery, including facial rejuvenation, hair removal and skin resurfacing -Use of lasers and other light sources for cosmetic and dermatological treatment -Applications of peeling agents, fillers, injectables, implants and other cosmetic modalities -Topical treatments -Practical tips and safety issues
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