Current role of Nuclear Medicine in the diagnosis and therapy of gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Hellenic journal of nuclear medicine Pub Date : 2023-05-01
Alexandros Georgakopoulos
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引用次数: 0

Abstract

Neuroendocrine tumors (NETs), are heterogenic neoplasms that arise from the disseminated endocrine cell system, primarily from gastroenteropancreatic (GEP) organs. Nuclear Medicine has a central role in both diagnosis and treatment of GEP-NETs. Somatostatin receptor scintigraphy (SRS) is still performed with SPECT/CT in case that PET/CT is not available but numerous studies have demonstrated the superior diagnostic accuracy of the latter for GEP-NETs. 68Ga -Dota peptide PET/CT (SSA-PET/CT) has high sensitivity, specificity and accuracy (86%-100%) and is recommended for the staging as also for the restaging of GEP-NETs.

核医学在胃肠胰神经内分泌肿瘤(GEP-NETs)诊断和治疗中的当前作用。
神经内分泌肿瘤(NETs)是一种起源于播散性内分泌细胞系统的异质性肿瘤,主要来自胃肠胰(GEP)器官。核医学在GEP NETs的诊断和治疗中发挥着核心作用。在PET/CT不可用的情况下,生长抑素受体闪烁扫描(SRS)仍然使用SPECT/CT进行,但许多研究已经证明后者对GEP-NETs具有优越的诊断准确性。68Ga-Dota肽PET/CT(SSA-PET/CT)具有高灵敏度、特异性和准确性(86%-100%),建议用于GEP-NETs的分期和再分期。
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来源期刊
CiteScore
1.40
自引率
6.70%
发文量
34
审稿时长
>12 weeks
期刊介绍: The Hellenic Journal of Nuclear Medicine published by the Hellenic Society of Nuclear Medicine in Thessaloniki, aims to contribute to research, to education and cover the scientific and professional interests of physicians, in the field of nuclear medicine and in medicine in general. The journal may publish papers of nuclear medicine and also papers that refer to related subjects as dosimetry, computer science, targeting of gene expression, radioimmunoassay, radiation protection, biology, cell trafficking, related historical brief reviews and other related subjects. Original papers are preferred. The journal may after special agreement publish supplements covering important subjects, dully reviewed and subscripted separately.
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