Examining the Use of HIV Self-Testing to Support PrEP Delivery: a Systematic Literature Review.

IF 3.7 2区医学 Q2 INFECTIOUS DISEASES

Current HIV/AIDS Reports Pub Date : 2022-10-01 DOI:10.1007/s11904-022-00617-x

Catherine Kiptinness, Alexandra P Kuo, Adriana M Reedy, Cheryl C Johnson, Kenneth Ngure, Anjuli D Wagner, Katrina F Ortblad

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引用次数: 6

Abstract

Purpose of review: HIV self-testing (HIVST) has the potential to expand access to and uptake of HIV pre-exposure prophylaxis (PrEP) delivery. We conducted a systematic literature review to understand the evidence on HIVST use for PrEP delivery.

Recent findings: After screening 1055 records, we included eight: three randomized trials and five values and preferences studies. None measured PrEP initiation. Most studies occurred in Sub-Saharan Africa (7/8) and included different populations. One trial found that HIVST use between quarterly clinic visits as part of an adherence package with biofeedback slightly increased adherence; the other two trials found that HIVST use between or in lieu of quarterly clinic visits had no significant or non-inferior effects on adherence. HIVST to support PrEP delivery was acceptable, feasible, and preferred. HIVST use for PrEP continuation largely resulted in similar outcomes to standard-of-care delivery and was perceived acceptable and feasible. Further research is needed to optimize HIVST use within PrEP programming.

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检查使用艾滋病毒自我检测来支持PrEP的提供:系统的文献综述。

审查目的:艾滋病毒自检(HIVST)有可能扩大艾滋病毒暴露前预防(PrEP)的可及性和接受程度。我们进行了系统的文献综述，以了解艾滋病毒传播用于预防分娩的证据。最近的发现:在筛选了1055个记录后，我们纳入了8个:3个随机试验和5个价值观和偏好研究。没有测量PrEP起始。大多数研究发生在撒哈拉以南非洲(7/8)，包括不同的人口。一项试验发现，作为生物反馈治疗方案的一部分，在每季度门诊就诊之间使用艾滋病毒检测技术略微增加了依从性;另外两项试验发现，在每季度就诊之间或代替就诊期间使用艾滋病毒检测技术对依从性没有显著或非次要的影响。艾滋病毒传播支持PrEP的提供是可接受的、可行的和首选的。继续使用艾滋病毒传播治疗PrEP的结果与标准护理提供的结果大致相似，并且被认为是可接受和可行的。需要进一步的研究来优化PrEP规划中艾滋病毒传播的使用。

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来源期刊

Current HIV/AIDS Reports INFECTIOUS DISEASES-

CiteScore

8.10

自引率

2.20%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of HIV/AIDS. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as antiretroviral therapies, behavioral aspects of management, and metabolic complications and comorbidity. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.