Effect of Early Balloon Inflation of Balloon Guide Catheter in Mechanical Thrombectomy for Large Vessel Occlusion.

IF 2 4区医学 Q3 CLINICAL NEUROLOGY

Current neurovascular research Pub Date : 2023-01-01 DOI:10.2174/1567202620666230404125627

Beom Mo Kang, Ho Jun Yi, Dong-Seong Shin, Bum-Tae Kim

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引用次数: 0

Abstract

Objective: A balloon guide catheter (BGC) is widely used in mechanical thrombectomy (MT). However, the balloon inflation timing of BGC has not been clearly established. We evaluated whether balloon inflation timing of BGC affects the results of MT.

Methods: Patients who underwent MT with BGC for anterior circulation occlusion were enrolled. Patients were dichotomized into early and late balloon inflation groups, according to the timing of BGC inflation. Angiographic and clinical outcomes were compared between the two groups. Multivariable analyses were performed to evaluate the predictive factors for first-pass reperfusion (FPR) and successful reperfusion (SR).

Results: Of 436 patients, the early balloon inflation group showed a shorter procedure time (21 min (11-37) vs. 29 min (14-46), p = 0.014), a higher rate of SR with aspiration only (64.0% vs. 55.4%, p = 0.016), a lower aspiration catheter delivery failure rate (11.1% vs. 19.4%, p = 0.005), less frequent technique conversion (36.0% vs. 44.5%, p = 0.009), higher rate of FPR (58.2% vs. 50.2%, p = 0.011), and a lower rate of distal embolization (7.9% vs. 11.7%, P = 0.006), compared to the late balloon inflation group. In multivariate analysis, early balloon inflation was an independent predictor for FPR (odds ratio, OR 1.53, 95% confidence interval, CI 1.37-2.57; p = 0.011) and SR (OR 1.26, 95% CI 1.18-1.64; p = 0.018).

Conclusion: Early balloon inflation of BGC enables an effective procedure than late balloon inflation. Early balloon inflation was associated with higher rates of FPR and SR.

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球囊导尿管早期球囊充气在大血管闭塞机械取栓中的作用。

目的:球囊导尿管在机械取栓术中应用广泛。然而，BGC的气球膨胀时间尚未明确确定。我们评估了BGC的球囊充气时机是否会影响MT的结果。方法:纳入了前循环闭塞的BGC行MT的患者。根据BGC充气时间将患者分为早期和晚期气囊充气组。比较两组血管造影和临床结果。采用多变量分析评价首次再灌注(FPR)和成功再灌注(SR)的预测因素。结果:的436名患者,早期的气球膨胀组显示过程时间短(21分钟(11-37)和29分钟(14-46),p = 0.014),较高的SR愿望只有(64.0%比55.4%,p = 0.016),较低的愿望导管输送失败率(11.1%比19.4%,p = 0.005),减少频繁的技术转换(36.0%比44.5%,p = 0.009),更高的玻璃钢(58.2%比50.2%,p = 0.011),和远端栓塞率较低(7.9%比11.7%,p = 0.006),与后期气球膨胀组相比。在多变量分析中，早期气球膨胀是FPR的独立预测因子(优势比，OR 1.53, 95%可信区间，CI 1.37-2.57;p = 0.011)和SR (OR 1.26, 95% CI 1.18-1.64;P = 0.018)。结论:早期球囊充气术比晚期球囊充气术更有效。早期气球膨胀与较高的FPR和SR率有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current neurovascular research 医学-临床神经学

CiteScore

3.80

自引率

9.50%

发文量

审稿时长

3 months

期刊介绍： Current Neurovascular Research provides a cross platform for the publication of scientifically rigorous research that addresses disease mechanisms of both neuronal and vascular origins in neuroscience. The journal serves as an international forum publishing novel and original work as well as timely neuroscience research articles, full-length/mini reviews in the disciplines of cell developmental disorders, plasticity, and degeneration that bridges the gap between basic science research and clinical discovery. Current Neurovascular Research emphasizes the elucidation of disease mechanisms, both cellular and molecular, which can impact the development of unique therapeutic strategies for neuronal and vascular disorders.