Biosynthesis of Quantum Dots and Their Therapeutic Applications in the Diagnosis and Treatment of Cancer and SARS-CoV-2.

IF 3.1 Q2 PHARMACOLOGY & PHARMACY

Advanced pharmaceutical bulletin Pub Date : 2023-07-01 DOI:10.34172/apb.2023.065

Musa Moetasam Zorab, Navid Mohammadjani, Morahem Ashengroph, Mehran Alavi

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引用次数: 1

Abstract

Quantum dots (QDs) are semiconductor materials that range from 2 nm to 10 nm. These nanomaterials (NMs) are smaller and have more unique properties compared to conventional nanoparticles (NPs). One of the unique properties of QDs is their special optoelectronic properties, making it possible to apply these NMs in bioimaging. Different size and shape QDs, which are used in various fields such as bioimaging, biosensing, cancer therapy, and drug delivery, have so far been produced by chemical methods. However, chemical synthesis provides expensive routes and causes serious environmental and health issues. Therefore, various biological systems such as bacteria, fungi, yeasts, algae, and plants are considered as potent eco-friendly green nanofactories for the biosynthesis of QDs, which are both economic and environmentally safe. The review aims to provide a descriptive overview of the various microbial agents for the synthesis of QDs and their biomedical applications for the diagnosis and treatment of cancer and SARS-CoV-2.

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量子点的生物合成及其在癌症和SARS-CoV-2诊断和治疗中的应用

量子点(QDs)是波长从2纳米到10纳米的半导体材料。与传统纳米颗粒相比，这些纳米材料(NMs)体积更小，具有更多独特的性能。量子点的独特性质之一是其特殊的光电性质，这使得这些纳米粒子在生物成像中的应用成为可能。不同大小和形状的量子点，用于生物成像、生物传感、癌症治疗和药物输送等各个领域，迄今为止都是通过化学方法生产出来的。然而，化学合成提供了昂贵的路线，并造成严重的环境和健康问题。因此，细菌、真菌、酵母、藻类和植物等各种生物系统被认为是生物合成量子点的有效的生态友好型绿色纳米工厂，既经济又环保。本文综述了用于合成量子点的各种微生物制剂及其在癌症和SARS-CoV-2的诊断和治疗中的生物医学应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced pharmaceutical bulletin PHARMACOLOGY & PHARMACY-

CiteScore

6.80

自引率

2.80%

发文量

审稿时长

12 weeks