IL-17A and IL-17F polymorphisms and asthma risk: A meta-analysis

IF 2.3 4区医学 Q3 GENETICS & HEREDITY

International Journal of Immunogenetics Pub Date : 2023-02-13 DOI:10.1111/iji.12616

Young Ho Lee

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引用次数: 0

Abstract

Thank you for your comment on the publication ‘Associations between interleukin 17A and 17F polymorphisms and asthma susceptibility: A meta-analysis’ (Lee & Song, 2023). Your suggestion to focus on the effects of unexpected and potentially confounding genetic variations in future research is particularly important in light of the complexity and ongoing nature of the field of genetic research. As you pointed out, asthma is a complex disease with multiple contributing factors, and it is crucial that future research takes a comprehensive approach in order to fully understand the underlying mechanisms of the disease (Toskala & Kennedy, 2015). By focusing on unexpected and potentially confounding genetic variations, we can expand our understanding of the genetic factors associated with asthma susceptibility and identify new therapeutic targets for the treatment of this condition (Friedrich et al., 2022). Your suggestion is particularly important given the rapid advancements in genetic research and the emergence of new technologies that allow for the identification and characterization of genetic variations. By utilizing these technologies, future research can more efficiently identify novel genetic variations that may be associated with asthma susceptibility, as well as better explain the functional implications of these variations. We will take your suggestion into consideration as we continue to advance our understanding of the genetic factors associated with asthma susceptibility. Young Ho Lee

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IL-17A和IL-17F多态性与哮喘风险:一项荟萃分析

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来源期刊

International Journal of Immunogenetics 医学-免疫学

CiteScore

4.70

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The International Journal of Immunogenetics (formerly European Journal of Immunogenetics) publishes original contributions on the genetic control of components of the immune system and their interactions in both humans and experimental animals. The term ''genetic'' is taken in its broadest sense to include studies at the evolutionary, molecular, chromosomal functional and population levels in both health and disease. Examples are: -studies of blood groups and other surface antigens- cell interactions and immune response- receptors, antibodies, complement components and cytokines- polymorphism- evolution of the organisation, control and function of immune system components- anthropology and disease associations- the genetics of immune-related disease: allergy, autoimmunity, immunodeficiency and other immune pathologies- All papers are seen by at least two independent referees and only papers of the highest quality are accepted.