Quality of life assessment in the first episode of acute coronary syndrome.

Smitha Pernaje Seetharam, Vinutha Shankar, Kaviraja Udupa, Raveesha Anjanappa, Niranjan Reddy
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Abstract

Background: Assessment of health-related quality of life (HRQoL) is an important measure of a patient's recovery after an illness. However, HRQoL among acute coronary syndrome (ACS) survivors has not been extensively studied following cardiac management.

Aim: The purpose of this study was to assess the quality of life (QoL) among ACS patients who have undergone percutaneous coronary intervention (PCI).

Methods: This cohort study included 145 consecutive male ACS patients between March 2021 and May 2022. Of these patients, 138 (mean age 54.3 ± 10.7 years) completed the QoL assessment using the short form-12 (SF-12) health survey questionnaire. Seventy (51%) of them presented with ST-segment elevation myocardial infarction (STEMI), 18 (13%) had non-STEMI, 39 (28%) had evolved MI, and 11 (8%) had unstable angina. Recruited patients' QoL data were assessed at various time points post-PCI.

Results: At the end of the 12 months of follow-up, major clinical events (MCE) defined as death, sudden death, or re-acute myocardial infarction occurred in 54.9% of patients. Out of 7 MCE, four deaths and three re-AMIs had occurred. SF-12 physical component score was found to be significantly improved when compared to the mental component score, which seems to improve without reaching statistical significance over time. Among event-free ACS patients, we found a significant positive correlation between left ventricular ejection fraction and HRQoL.

Conclusion: Improvement in HRQoL (physical component) was seen among ACS patients post-PCI.

Relevance for patients: QoL assessment outcomes should be considered in clinical settings, practice guidelines, and treatment modality post-PCI to improve QoL in post-ACS survivors.

Abstract Image

急性冠脉综合征首发患者的生活质量评价。
背景:健康相关生活质量评估(HRQoL)是衡量患者疾病后康复的重要指标。然而,急性冠脉综合征(ACS)幸存者的HRQoL在心脏治疗后尚未得到广泛研究。目的:本研究的目的是评估ACS患者经皮冠状动脉介入治疗(PCI)的生活质量(QoL)。方法:该队列研究纳入了2021年3月至2022年5月期间连续145例男性ACS患者。其中138例(平均年龄54.3±10.7岁)采用SF-12健康调查问卷完成生活质量评估。其中70例(51%)表现为st段抬高型心肌梗死(STEMI), 18例(13%)为非STEMI, 39例(28%)发展为心肌梗死,11例(8%)为不稳定型心绞痛。在pci后的不同时间点评估入选患者的生活质量数据。结果:在12个月的随访结束时,54.9%的患者发生了重大临床事件(MCE),定义为死亡、猝死或再急性心肌梗死。在7个特派团中,有4人死亡,3人被重新杀害。SF-12身体成分得分与精神成分得分相比有显著提高,随着时间的推移,精神成分得分似乎有所提高,但没有达到统计学意义。在无事件ACS患者中,我们发现左室射血分数与HRQoL显著正相关。结论:ACS患者行pci后HRQoL(物理指标)有明显改善。与患者的相关性:生活质量评估结果应在临床设置、实践指南和pci后治疗方式中考虑,以改善acs后幸存者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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