Potentials of Stem Cell Therapy in Patients Infected with COVID- 19: A Systematic Review.

Q3 Biochemistry, Genetics and Molecular Biology
Zahra Tamis, Fatemeh Sadeghi, Aigin Heydari, Saima Shahzad Mirza, Mohammad Hossein Morowvat
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Abstract

Introduction: In the present study, we have examined different aspects and potentials of stem cells for the management of patients infected with COVID-19.

Background: The novel coronavirus disease (COVID-19) has been reported in most of the countries and territories (>230) of the world with .686 million confirmed cases (as of Apr. 22, 2023). While the scientific community is working to develop vaccines and develop drugs against the COVID-19 pandemic, novel alternative therapies may reduce the mortality rate. Recently, the application of stem cells for critically ill COVID-19 patients in a small group of patients has been examined.

Methods: We searched PubMed, Web of Science, and Google Scholar up to July 2022. Those studies that reviewed COVID-19 and cell therapy potentials were entered into the study. Moreover, some recently published patents were exploited and reviewed. Patentscope, USPTO, Espacenet, Free Patents Online, and Google Patents were used for patent searches.

Results: Cell-based therapy as a modality of regenerative medicine is considered one of the most promising disciplines in the fields of modern science and medicine. Such an advanced technology offers endless possibilities for transformative and potentially curative treatments for some of the most life-threatening diseases. This therapeutic tool can be useful to reduce the rate of mortality. There have been several published patents for different stem cell therapy platforms in recent years.

Conclusion: Stem cell therapy could be considered a safe and effective therapeutic strategy to reduce death cases in patients infected with COVID-19. Besides, stem cell therapy might increase the pulmonary functions in the patients, it suppresses the occurring inflammations and ameliorates the symptoms.

干细胞疗法在 COVID- 19 感染者中的应用潜力:系统综述。
简介在本研究中,我们研究了干细胞治疗COVID-19感染者的不同方面和潜力:新型冠状病毒病(COVID-19)已在全球大多数国家和地区(超过230个)报告,确诊病例达6.86亿例(截至2023年4月22日)。尽管科学界正在努力开发疫苗和药物来应对 COVID-19 大流行,但新型替代疗法可能会降低死亡率。最近,研究人员对一小部分 COVID-19 重症患者应用干细胞进行了研究:我们搜索了截至 2022 年 7 月的 PubMed、Web of Science 和 Google Scholar。方法:我们检索了截至 2022 年 7 月的 PubM、Web Science 和谷歌学术,其中包括对 COVID-19 和细胞疗法潜力进行了综述的研究。此外,我们还利用并审查了一些近期发表的专利。专利检索使用了Patentscope、美国专利商标局、Espacenet、免费专利在线和谷歌专利:结果:细胞疗法作为一种再生医学模式,被认为是现代科学和医学领域最有前途的学科之一。这种先进的技术为治疗一些威胁生命的疾病提供了无限的可能性。这种治疗工具可以有效降低死亡率。近年来,不同的干细胞疗法平台已公布了多项专利:结论:干细胞疗法可被视为一种安全有效的治疗策略,可减少COVID-19感染者的死亡病例。此外,干细胞疗法可增强患者的肺功能,抑制炎症,改善症状。
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来源期刊
Recent patents on biotechnology
Recent patents on biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
2.90
自引率
0.00%
发文量
51
期刊介绍: Recent Patents on Biotechnology publishes review articles by experts on recent patents on biotechnology. A selection of important and recent patents on biotechnology is also included in the journal. The journal is essential reading for all researchers involved in all fields of biotechnology.
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