In-plane and out-of-plane gigahertz sound velocities of saturated and unsaturated phospholipid bilayers from cryogenic to room temperatures

IF 3.4 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Chemistry and Physics of Lipids Pub Date : 2023-10-01 DOI:10.1016/j.chemphyslip.2023.105335

E.A. Dobrynina, V.A. Zykova, N.V. Surovtsev

引用次数: 0

Abstract

Here, we examined the gigahertz sound velocities of hydrated multibilayers of saturated (1,2-dimyristoyl-sn-glycero-3-phosphocholine, DMPC) and unsaturated (1,2-dioleoyl-sn-glycero-3-phosphocholine, DOPC) phospholipids by Brillouin spectroscopy. Out-of-plane and in-plane (lateral) phonons were studied independently of each other. Similar strong temperature dependences of the sound velocities were found for phonons of both types. The sound velocities in the low-temperature limit were two-fold higher than that at physiological temperatures; a significant part of the changes in sound velocity occurs in the solid-like gel phase. The factors that may be involved in the peculiar behavior of sound velocity include changes in the chain conformational state, relaxation susceptibility, changes in the elastic modulus at infinite frequencies, and lateral packing of molecules.

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饱和和不饱和磷脂双层从低温到室温的平面内和平面外千兆赫声速。

在这里，我们通过布里渊光谱检测了饱和（1,2-二巯基-sn-甘油-3-磷酸胆碱，DMPC）和不饱和（1,2-dioeoyl-sn-甘油-3-磷胆碱，DOPC）磷脂的水合多双层的千兆赫声速。平面外和平面内（横向）声子相互独立地进行了研究。对于这两种类型的声子，都发现了类似的强烈的声速温度依赖性。低温极限下的声速比生理温度下的声速高出两倍；声速变化的很大一部分发生在类固体凝胶相中。声速的特殊行为可能涉及的因素包括链构象状态的变化、弛豫易感性、无限频率下弹性模量的变化以及分子的横向堆积。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemistry and Physics of Lipids 生物-生化与分子生物学

CiteScore

7.60

自引率

2.90%

发文量

审稿时长

40 days

期刊介绍： Chemistry and Physics of Lipids publishes research papers and review articles on chemical and physical aspects of lipids with primary emphasis on the relationship of these properties to biological functions and to biomedical applications. Accordingly, the journal covers: advances in synthetic and analytical lipid methodology; mass-spectrometry of lipids; chemical and physical characterisation of isolated structures; thermodynamics, phase behaviour, topology and dynamics of lipid assemblies; physicochemical studies into lipid-lipid and lipid-protein interactions in lipoproteins and in natural and model membranes; movement of lipids within, across and between membranes; intracellular lipid transfer; structure-function relationships and the nature of lipid-derived second messengers; chemical, physical and functional alterations of lipids induced by free radicals; enzymatic and non-enzymatic mechanisms of lipid peroxidation in cells, tissues, biofluids; oxidative lipidomics; and the role of lipids in the regulation of membrane-dependent biological processes.