Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome (PCOS): A Comprehensive Review.

IF 4.6 3区医学 Q1 NUTRITION & DIETETICS

Current Nutrition Reports Pub Date : 2023-09-01 DOI:10.1007/s13668-023-00479-8

M Di Lorenzo, N Cacciapuoti, M S Lonardo, G Nasti, C Gautiero, A Belfiore, B Guida, M Chiurazzi

{"title":"Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome (PCOS): A Comprehensive Review.","authors":"M Di Lorenzo, N Cacciapuoti, M S Lonardo, G Nasti, C Gautiero, A Belfiore, B Guida, M Chiurazzi","doi":"10.1007/s13668-023-00479-8","DOIUrl":null,"url":null,"abstract":"Purpose of review: Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in women of reproductive age worldwide. This disease causes menstrual, metabolic, and biochemical abnormalities such as hyperandrogenism, oligo-anovulatory menstrual cycles, polycystic ovary, hyperleptinemia, insulin resistance (IR), and cardiometabolic disorders, often associated with overweight or obesity and visceral adiposity.Recent findings: The etiology and pathophysiology of PCOS are not yet fully understood, but insulin seems to play a key role in this disease. PCOS shares an inflammatory state with other chronic diseases such as obesity, type II diabetes, and cardiovascular diseases; however, recent studies have shown that a healthy nutritional approach can improve IR and metabolic and reproductive functions, representing a valid therapeutic strategy to ameliorate PCOS symptomatology. This review aimed to summarize and collect evidence about different nutritional approaches such as the Mediterranean diet (MedDiet) and the ketogenic diet (KD), as well as bariatric surgery and nutraceutical supplementation as probiotics, prebiotics, and synbiotics, among the others, used in patients with PCOS.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444658/pdf/","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Nutrition Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s13668-023-00479-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}

引用次数: 2

Abstract

Purpose of review: Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in women of reproductive age worldwide. This disease causes menstrual, metabolic, and biochemical abnormalities such as hyperandrogenism, oligo-anovulatory menstrual cycles, polycystic ovary, hyperleptinemia, insulin resistance (IR), and cardiometabolic disorders, often associated with overweight or obesity and visceral adiposity.

Recent findings: The etiology and pathophysiology of PCOS are not yet fully understood, but insulin seems to play a key role in this disease. PCOS shares an inflammatory state with other chronic diseases such as obesity, type II diabetes, and cardiovascular diseases; however, recent studies have shown that a healthy nutritional approach can improve IR and metabolic and reproductive functions, representing a valid therapeutic strategy to ameliorate PCOS symptomatology. This review aimed to summarize and collect evidence about different nutritional approaches such as the Mediterranean diet (MedDiet) and the ketogenic diet (KD), as well as bariatric surgery and nutraceutical supplementation as probiotics, prebiotics, and synbiotics, among the others, used in patients with PCOS.

Abstract Image

查看原文本刊更多论文

多囊卵巢综合征(PCOS)的病理生理和营养途径:综合综述。

综述目的:多囊卵巢综合征(PCOS)是世界范围内育龄妇女最常见的内分泌代谢疾病。这种疾病导致月经、代谢和生化异常，如雄激素过多、少排卵月经周期、多囊卵巢、高瘦素血症、胰岛素抵抗(IR)和心脏代谢紊乱，通常与超重或肥胖和内脏肥胖有关。最近发现:多囊卵巢综合征的病因和病理生理尚不完全清楚，但胰岛素似乎在这种疾病中起关键作用。多囊卵巢综合征与其他慢性疾病如肥胖、II型糖尿病和心血管疾病有共同的炎症状态;然而，最近的研究表明，健康的营养方法可以改善IR、代谢和生殖功能，是改善多囊卵巢综合征症状的有效治疗策略。本综述旨在总结和收集关于不同营养方法的证据，如地中海饮食(MedDiet)和生酮饮食(KD)，以及减肥手术和营养补充剂作为益生菌、益生元和合成菌等，用于多囊卵巢综合征患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Nutrition Reports Agricultural and Biological Sciences-Food Science

CiteScore

7.70

自引率

2.00%

发文量

期刊介绍： This journal aims to provide comprehensive review articles that emphasize significant developments in nutrition research emerging in recent publications. By presenting clear, insightful, balanced contributions by international experts, the journal intends to discuss the influence of nutrition on major health conditions such as diabetes, cardiovascular disease, cancer, and obesity, as well as the impact of nutrition on genetics, metabolic function, and public health. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 25 internationally diverse members reviews the annual table of contents, suggests topics of special importance to their country/region, and ensures that topics and current and include emerging research.

文献相关原料

公司名称	产品信息	采购帮参考价格