Dementia Prevalence and Risk Factors: Data From Rural Tanzania.

IF 1.8 4区医学 Q3 CLINICAL NEUROLOGY

Alzheimer Disease & Associated Disorders Pub Date : 2023-07-01 Epub Date: 2023-07-10 DOI:10.1097/WAD.0000000000000564

Caitlin Roe, Ssenku Safic, Lwitiko Mwaipopo, Catherine L Dotchin, Joanna Klaptocz, William Gray, Marcyella Joseph, Aimee Spector, Sarah Urasa, Richard W Walker

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引用次数: 0

Abstract

Objectives: The burden of dementia is increasing in sub-Saharan Africa (SSA), but there are limited epidemiological data on dementia in SSA. This study investigated the prevalence and associations of dementia in older adults (less than 60 y) attending the outpatient department of Mount Meru Hospital in Tanzania.

Methods: This one-phase cross-sectional study screened a sample using the Identification of Dementia in Elderly Africans (IDEA) cognitive screening tool. Those that screened as having possible and probable dementia were further assessed, and diagnosis of dementia was made according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). Demographic and risk factor data were collected.

Results: Within those screened, 57/1141 (5.0%) (95% CI: 3.7-6.3) had dementia. Female sex [odds ratio (OR)=2.778, 95% CI: 1.074-7.189], having never attended school (OR=6.088, 95% CI: 1.360-27.256), alcohol (U/wk) (OR=1.080, 95% CI: 1.016-1.149), uncorrected visual impairment (OR=4.260, 95% CI: 1.623-11.180), body mass index <18.5 kg/m 2 (OR=6.588, 95% CI: 2.089-20.775), and stroke (OR=15.790, 95% CI: 3.48-74.475) were found to be significantly, independently associated with dementia.

Conclusions: The prevalence of dementia in this population is similar to a recent community-based rate in Tanzania and lower than a hospital-based rate in Senegal. This is the first time the association between visual impairment and dementia has been reported in SSA. Other associations are in keeping with previous literature.

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痴呆症患病率和危险因素：坦桑尼亚农村的数据。

目标：撒哈拉以南非洲地区的痴呆症负担正在增加，但关于撒哈拉以南地区痴呆症的流行病学数据有限。这项研究调查了在坦桑尼亚梅鲁山医院门诊就诊的老年人（60岁以下）患痴呆症的患病率和相关性。方法：这项一阶段横断面研究使用非洲老年痴呆症识别（IDEA）认知筛查工具对样本进行筛查。对那些被筛查为可能和可能患有痴呆症的人进行了进一步评估，并根据《精神障碍诊断和统计手册》第四版（DSM-IV）对痴呆症进行了诊断。收集人口统计学和危险因素数据。结果：在筛选的患者中，57/1141（5.0%）（95%CI:3.7-6.3）患有痴呆症。女性[比值比（OR）=2.778，95%CI:1.074-7.189]，从未上过学（OR=6.088，95%CI:1.360-27.256），饮酒（U/wk）（OR=1.080，95%CI:1.016-1.149），未矫正视力障碍（OR=4.260，95%CI:1.623-11.180），体重指数结论：该人群中痴呆症的患病率与坦桑尼亚最近的社区发病率相似，低于塞内加尔的医院发病率。这是SSA首次报道视觉障碍与痴呆之间的关联。其他关联与以前的文献一致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Alzheimer Disease & Associated Disorders 医学-病理学

CiteScore

3.10

自引率

4.80%

发文量

期刊介绍： Alzheimer Disease & Associated Disorders is a peer-reviewed, multidisciplinary journal directed to an audience of clinicians and researchers, with primary emphasis on Alzheimer disease and associated disorders. The journal publishes original articles emphasizing research in humans including epidemiologic studies, clinical trials and experimental studies, studies of diagnosis and biomarkers, as well as research on the health of persons with dementia and their caregivers. The scientific portion of the journal is augmented by reviews of the current literature, concepts, conjectures, and hypotheses in dementia, brief reports, and letters to the editor.