Gastric juvenile polyposis syndrome with inflammatory changes in the intervening mucosa.

IF 2.5 4区医学 Q2 PATHOLOGY

Pathology International Pub Date : 2023-11-01 Epub Date: 2023-08-22 DOI:10.1111/pin.13374

Mitsuhiro Nikaido, Takafumi Takimoto, Takaki Sakurai, Masahito Hoki, Sachiko Minamiguchi, Takeshi Nakajima, Masako Torishima, Tatsuto Nishigori, Kazutaka Obama, Yukari Koyama, Tsutomu Chiba, Mineko Ushiama, Masahiro Gotoh, Mari Teramura, Haruhiko Takeda, Takahiro Shimizu, Hiroshi Seno

引用次数: 1

Abstract

Juvenile polyposis syndrome (JPS) is an autosomal dominant inherited disorder characterized by multiple hamartomatous polyps in the gastrointestinal tract, and is caused by germline mutations in SMAD4 or BMPR1A. 1 However, no pathogenic variant is found in 40% of cases, and one-fourth of cases occur without a family history. Multiple polyps are typically found in the colon (98%), stomach (14%), duodenum (7%), jejunum, and ileum (7%). This article is protected by copyright. All rights reserved.

查看原文本刊更多论文

胃少年性息肉病综合征，其间黏膜有炎性改变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Pathology International 医学-病理学

CiteScore

4.50

自引率

4.50%

发文量

102

审稿时长

12 months

期刊介绍： Pathology International is the official English journal of the Japanese Society of Pathology, publishing articles of excellence in human and experimental pathology. The Journal focuses on the morphological study of the disease process and/or mechanisms. For human pathology, morphological investigation receives priority but manuscripts describing the result of any ancillary methods (cellular, chemical, immunological and molecular biological) that complement the morphology are accepted. Manuscript on experimental pathology that approach pathologenesis or mechanisms of disease processes are expected to report on the data obtained from models using cellular, biochemical, molecular biological, animal, immunological or other methods in conjunction with morphology. Manuscripts that report data on laboratory medicine (clinical pathology) without significant morphological contribution are not accepted.