Many leveled ordinal models for frequency of alcohol and drug use.

IF 2.7 3区 医学 Q2 PSYCHOLOGY, CLINICAL
Mark S Chambers, Christopher Drovandi
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引用次数: 0

Abstract

Background: The numbers of days people consume alcohol and other drugs over a fixed interval, such as 28 days, are often collected in surveys of substance use. The presence of an upper bound on these variables can result in response distributions with "ceiling effects." Also, if some peoples' substance use behaviors are characterized by weekly patterns of use, summaries of substance days-of-use over longer periods can exhibit multiple modes.Objective: To highlight advantages of ordinal models with a separate level for each distinct survey response, for bounded, and potentially multimodal, count data.Methods: We fitted a Bayesian proportional odds ordinal model to longitudinal cannabis days-of-use reported by 443 individuals who used illicit drugs (206 female, 214 male, 23 non-binary). We specified an ordinal level for each unique response to allow the exact numeric distribution implied by the predicted ordinal response to be inferred. We then compared the fit of the proportional odds model with binomial, negative binomial, hurdle negative binomial and beta-binomial models.Results: Posterior predictive checks and the leave one out information criterion both suggested that the proportional odds model gave a better fit to the cannabis days-of-use data than the other models. Cannabis use among the target population declined during the COVID-19 pandemic in Australia, with the odds of a member of the population exceeding any specified frequency of cannabis use in Wave 4 estimated to be 73% lower than in Wave 1 (median odds ratio 0.27, 90% credible interval 0.19, 0.38).Conclusion: Ordinal models can be suitable for complex count data.

许多关于酒精和药物使用频率的分级顺序模型。
背景:人们在固定间隔(如28天)内消费酒精和其他药物的天数通常在物质使用调查中收集。这些变量的上界的存在会导致具有“天花板效应”的响应分布。此外,如果某些人的物质使用行为以每周使用模式为特征,则较长时期内物质使用天数的摘要可以表现出多种模式。目的:突出顺序模型的优势,为每个不同的调查响应提供单独的水平,对于有界的,可能是多模态的计数数据。方法:采用贝叶斯比例odds序数模型拟合443例吸毒个体(女性206例,男性214例,非二元23例)的纵向大麻使用天数。我们为每个唯一响应指定了一个序数级别,以允许推断预测的序数响应所隐含的精确数字分布。然后,我们比较了比例赔率模型与二项、负二项、障碍负二项和β二项模型的拟合。结果:后验预测检验和留一信息准则均表明,比例赔率模型比其他模型更适合大麻使用天数数据。在澳大利亚2019冠状病毒病大流行期间,目标人群的大麻使用量有所下降,在第4波中,人口中某一成员超过任何特定频率使用大麻的几率估计比第1波低73%(中位优势比0.27,90%可信区间0.19,0.38)。结论:有序模型适用于复杂的计数数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.70
自引率
3.70%
发文量
68
期刊介绍: The American Journal of Drug and Alcohol Abuse (AJDAA) is an international journal published six times per year and provides an important and stimulating venue for the exchange of ideas between the researchers working in diverse areas, including public policy, epidemiology, neurobiology, and the treatment of addictive disorders. AJDAA includes a wide range of translational research, covering preclinical and clinical aspects of the field. AJDAA covers these topics with focused data presentations and authoritative reviews of timely developments in our field. Manuscripts exploring addictions other than substance use disorders are encouraged. Reviews and Perspectives of emerging fields are given priority consideration. Areas of particular interest include: public health policy; novel research methodologies; human and animal pharmacology; human translational studies, including neuroimaging; pharmacological and behavioral treatments; new modalities of care; molecular and family genetic studies; medicinal use of substances traditionally considered substances of abuse.
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