Clinical Features and Outcomes of ICU Patients Confirmed with COVID-19 Infection in Bandar Abbas, Iran: A Single-Centered Retrospective Study.

Q3 Medicine
Tanaffos Pub Date : 2022-04-01
Hamideh Estabraghnia Babaki, Hashem Jarineshin, Fateme Saljoughi, Mehdi Hassaniazad, Shideh Rafati, Shahla Sohrabipour
{"title":"Clinical Features and Outcomes of ICU Patients Confirmed with COVID-19 Infection in Bandar Abbas, Iran: A Single-Centered Retrospective Study.","authors":"Hamideh Estabraghnia Babaki,&nbsp;Hashem Jarineshin,&nbsp;Fateme Saljoughi,&nbsp;Mehdi Hassaniazad,&nbsp;Shideh Rafati,&nbsp;Shahla Sohrabipour","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The clinical characteristics of COVID-19 are diverse from a simple common cold symptom to acute respiratory distress syndrome (ARDS). In the present study, we attempted to identify the associated factors in surviving COVID-19 intensive care unit (ICU) patients based on their clinical characteristics.</p><p><strong>Materials and methods: </strong>This retrospective study was performed on 114 laboratory-confirmed COVID-19 patients admitted to the intensive care units of Hormozgan University of Medical Sciences, Iran. Demographic, medical, clinical manifestations at admission time, and outcome data were obtained from the patient's medical records.</p><p><strong>Results: </strong>Of 114 participants included in this study, 64.9% were men. Their mean age was approximately 54 years old, 69.3% of them died and 30.7% of them were discharged. The mortality rate was 2.96 times higher in people who had ARDS compared to their counterparts, 1.37 times higher in people under non-invasive ventilation, and 3.56 times higher in people under invasive mechanical ventilation.Three common underlying diseases among them were hypertension in 34.2%, diabetes in 23.7%, and cardiovascular diseases in 17.5% of them. Alive and dead patients significantly differed only in the following laboratory tests: D-dimer, urea, troponin, Procalcitonin, and ferritin.</p><p><strong>Conclusion: </strong>The mortality rate among COVID-19 patients admitted to ICU is generally high. Dyspnea, as the initial presentation and comorbidity, especially hypertension, diabetes, and cardiovascular diseases, may be associated with a higher risk of developing severe disease and consequent mortality. Therefore, D-dimer, urea, troponin, Procalcitonin, and ferritin at the time of hospital admission could predict the severity of the disease and its probable mortality.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/a0/Tanaffos-21-455.PMC10423860.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tanaffos","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Background: The clinical characteristics of COVID-19 are diverse from a simple common cold symptom to acute respiratory distress syndrome (ARDS). In the present study, we attempted to identify the associated factors in surviving COVID-19 intensive care unit (ICU) patients based on their clinical characteristics.

Materials and methods: This retrospective study was performed on 114 laboratory-confirmed COVID-19 patients admitted to the intensive care units of Hormozgan University of Medical Sciences, Iran. Demographic, medical, clinical manifestations at admission time, and outcome data were obtained from the patient's medical records.

Results: Of 114 participants included in this study, 64.9% were men. Their mean age was approximately 54 years old, 69.3% of them died and 30.7% of them were discharged. The mortality rate was 2.96 times higher in people who had ARDS compared to their counterparts, 1.37 times higher in people under non-invasive ventilation, and 3.56 times higher in people under invasive mechanical ventilation.Three common underlying diseases among them were hypertension in 34.2%, diabetes in 23.7%, and cardiovascular diseases in 17.5% of them. Alive and dead patients significantly differed only in the following laboratory tests: D-dimer, urea, troponin, Procalcitonin, and ferritin.

Conclusion: The mortality rate among COVID-19 patients admitted to ICU is generally high. Dyspnea, as the initial presentation and comorbidity, especially hypertension, diabetes, and cardiovascular diseases, may be associated with a higher risk of developing severe disease and consequent mortality. Therefore, D-dimer, urea, troponin, Procalcitonin, and ferritin at the time of hospital admission could predict the severity of the disease and its probable mortality.

伊朗阿巴斯港ICU确诊COVID-19感染患者的临床特征和结局:一项单中心回顾性研究
背景:COVID-19的临床特征多样,从单纯的普通感冒症状到急性呼吸窘迫综合征(ARDS)。在本研究中,我们试图根据COVID-19重症监护病房(ICU)存活患者的临床特征确定相关因素。材料与方法:对伊朗霍尔木兹甘医科大学重症监护病房收治的114例新冠肺炎实验室确诊患者进行回顾性研究。从患者的医疗记录中获得人口统计学、医学、入院时的临床表现和结局数据。结果:114名参与者中,男性占64.9%。平均年龄约54岁,死亡69.3%,出院30.7%。ARDS患者的死亡率是对照组的2.96倍,无创通气组的死亡率是1.37倍,有创机械通气组的死亡率是3.56倍。其中,高血压(34.2%)、糖尿病(23.7%)和心血管疾病(17.5%)是常见的3种基础疾病。活着和死去的患者只有在以下实验室测试中有显著差异:d -二聚体、尿素、肌钙蛋白、降钙素原和铁蛋白。结论:新型冠状病毒病死率普遍较高。呼吸困难,作为最初的表现和合并症,特别是高血压、糖尿病和心血管疾病,可能与发展成严重疾病和随之而来的死亡的高风险有关。因此,入院时d -二聚体、尿素、肌钙蛋白、原降钙素和铁蛋白可以预测疾病的严重程度及其可能的死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Tanaffos
Tanaffos Medicine-Critical Care and Intensive Care Medicine
CiteScore
1.10
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信