The relationship between visceral adipose index and resistant hypertension in people living with diabetes.

IF 2.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Gokhan Gökalp, Nail Burak Özbeyaz
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Abstract

Objective: Resistant hypertension (RHT) is a more risky HT phenotype in terms of mortality and morbidity. It is more common in people living with diabetes. Studies have shown that visceral adipose index (VAI), a new obesity parameter, is associated with HT and diabetes mellitus (DM). The association of VIA with RHT has not been previously evaluated. The aim of this study is to analyze the relationship between VAI and RHT in people living with diabetes.

Methods: We have conducted a single-center, retrospective study in patients with HT and DM (n = 557). Patients were divided into RHT (n = 274) and non-RHT (n = 283) groups. Patients using 3 or more antihypertensive drugs, one of which was a diuretic drug, were defined as RHT. VAIs of the patients were calculated according to gender.

Results: VAI was significantly higher in the RHT group compared to the non-RHT group (4.59 ± 2.77 vs. 3.73 ± 2.31, p < 0.001). Multivariate regression analysis revealed that coronary artery disease (OR 2.099 (1.327-3.318), p = 0.002), waist circumference (OR 1.043 (1.026-1.061), p < 0.001) and VAI (OR 1.216 (1.062-1.339), p = 0.005) were independent risk factors for the development of RHT in people living with diabetes. In addition, smoking, high triglyceride levels, and low high-density lipoprotein levels were among the predictive factors for RHT in people living with diabetes.

Conclusion: In our study, we have determined that increased VAI is an independent risk factor for RHT in people living with diabetes. VAI may have better ability to predict RHT than many other parameters.

糖尿病患者内脏脂肪指数与顽固性高血压的关系
目的:就死亡率和发病率而言,顽固性高血压(RHT)是一种更危险的HT表型。它在糖尿病患者中更为常见。研究表明,内脏脂肪指数(VAI)是一种新的肥胖参数,与HT和糖尿病(DM)有关。VIA与RHT的关系此前没有被评估过。本研究的目的是分析糖尿病患者VAI与RHT之间的关系。方法:我们对HT和DM患者进行了一项单中心回顾性研究(n = 557)。患者分为RHT组(n = 274)和非RHT组(n = 283)。使用3种及以上降压药物,其中1种为利尿剂的患者定义为RHT。按性别计算患者vis。结果:RHT组VAI显著高于非RHT组(4.59±2.77 vs. 3.73±2.31,p = 0.002),腰围(OR 1.043 (1.026-1.061), p = 0.005)是糖尿病患者发生RHT的独立危险因素。此外,吸烟、高甘油三酯水平和低高密度脂蛋白水平是糖尿病患者发生RHT的预测因素。结论:在我们的研究中,我们已经确定VAI升高是糖尿病患者RHT的独立危险因素。与许多其他参数相比,VAI可能具有更好的预测RHT的能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Postgraduate Medicine
Postgraduate Medicine 医学-医学:内科
CiteScore
6.10
自引率
2.40%
发文量
110
审稿时长
6-12 weeks
期刊介绍: Postgraduate Medicine is a rapid peer-reviewed medical journal published for physicians. Tracing its roots back to 1916,  Postgraduate Medicine  was established by Charles Mayo, MD, as a peer-to-peer method of communicating the latest research to aid physicians when making treatment decisions, and it maintains that aim to this day. In addition to its core subscriber base, Postgraduate Medicine is distributed to hundreds of US-based physicians within internal medicine and family practice.
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