American journal of physiology. Renal physiology

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American journal of physiology. Renal physiology - 最新文献

Renal ischemia/reperfusion injury triggers proximal tubular apoptosis and NHE3 dysfunction via p38MAPK/ezrin signaling pathway.

Pub Date : 2025-07-03 DOI: 10.1152/ajprenal.00338.2024 Juliana Martins da Costa-Pessoa, Mariana Charleaux de Ponte, Heitor Macedo Braz, Mário Costa Cruz, Guilherme Lopes Gonçalves, Maria Oliveira-Souza

Inhibition of methylthioadenosine phosphorylase protects from experimental acute kidney injury.

Pub Date : 2025-07-02 DOI: 10.1152/ajprenal.00138.2025 Afaf Saliba, Yidong Chen, Jonathan W Nelson, Abhinav Vetcha, Wei Wei Wang, Li Kang, Nagarjunachary Ragi, Soumya Maity, Hamid Rabb, W Brian Reeves, Kumar Sharma

Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental Polycystic Kidney Disease.

Pub Date : 2025-07-02 DOI: 10.1152/ajprenal.00056.2025 Humayra Afrin, Jielu Hao, Usama Qamar, Peter C Harris, Navin Gupta

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