Bioprocess and Biosystems Engineering

Bioprocess and Biosystems Engineering provides an international peer-reviewed forum to facilitate the discussion between engineering and biological science to find efficient solutions in the development and improvement of bioprocesses. The aim of the journal is to focus more attention on the multidisciplinary approaches for integrative bioprocess design. Of special interest are the rational manipulation of biosystems through metabolic engineering techniques to provide new biocatalysts as well as the model based design of bioprocesses (up-stream processing, bioreactor operation and downstream processing) that will lead to new and sustainable production processes. Contributions are targeted at new approaches for rational and evolutive design of cellular systems by taking into account the environment and constraints of technical production processes, integration of recombinant technology and process design, as well as new hybrid intersections such as bioinformatics and process systems engineering. Manuscripts concerning the design, simulation, experimental validation, control, and economic as well as ecological evaluation of novel processes using biosystems or parts thereof (e.g., enzymes, microorganisms, mammalian cells, plant cells, or tissue), their related products, or technical devices are also encouraged. The Editors will consider papers for publication based on novelty, their impact on biotechnological production and their contribution to the advancement of bioprocess and biosystems engineering science. Submission of papers dealing with routine aspects of bioprocess engineering (e.g., routine application of established methodologies, and description of established equipment) are discouraged.

《Bioprocess and Biosystems Engineering》是一本以工程技术-工程：化工综合研究为特色的国际期刊。该刊由SPRINGER出版商创刊于1986年，刊期Bimonthly。它提供了一个国际同行评审的论坛，以促进工程和生物科学之间的讨论，以找到生物过程开发和改进的有效解决方案。杂志的目的是更多地关注综合生物过程设计的多学科方法。特别令人感兴趣的是通过代谢工程技术对生物系统进行合理操纵，以提供新的生物催化剂，以及基于模型的生物过程设计（上游加工、生物反应器操作和下游加工），这将导致新的可持续生产过程。 贡献的目标是通过考虑技术生产过程的环境和限制、重组技术和工艺设计的整合以及生物信息学和工艺系统工程等新的混合交叉点，提出细胞系统的合理和进化设计的新方法。 涉及使用生物系统或其部分（例如酶、微生物、哺乳动物细胞、植物细胞或组织）、其相关产品或技术的新颖过程的设计、模拟、实验验证、控制和经济以及生态评估的手稿，技术装置也受到鼓励。