SLAS discovery : advancing life sciences R & D

A Scalable Human Gut-Immune Co-Culture Model for Evaluating Inflammatory Bowel Disease Anti-Inflammatory Therapies.

Pub Date : 2025-07-09 DOI: 10.1016/j.slasd.2025.100248 Swetha Peddibhotla, Lauren A Boone, Earnest Taylor, Bryan E McQueen, Elizabeth M Boazak

High-throughput screening for the identification of dual inhibitors of BRD4 and RIPK3 toward the development of small-molecule medical countermeasure agents against arsenicals.

Pub Date : 2025-07-02 DOI: 10.1016/j.slasd.2025.100247 Marina Fosso Yatchang, Ling Zhai, Omar Moukha-Chafiq, Bini Mathew, Fuad Ai Abir, Sixue Zhang, Pedro Ruiz, Sara McKellip, Miranda Nebane, Jake Y Chen, Anupam Agarwal, James R Bostwick, Mark J Suto, Mohammad Athar, Corinne E Augelli-Szafran

A high-throughput response to the SARS-CoV-2 pandemic.

Pub Date : 2024-07-01 DOI: 10.1016/j.slasd.2024.100160 Lynn Rasmussen, Shalisa Sanders, Melinda Sosa, Sara McKellip, N Miranda Nebane, Yohanka Martinez-Gzegozewska, Andrew Reece, Pedro Ruiz, Anna Manuvakhova, Ling Zhai, Brooke Warren, Aliyah Curry, Qinghua Zeng, J Robert Bostwick, Paige N Vinson