癌症耐药(英文)

Fibroblast growth factor receptor alterations and resistance mechanisms in the treatment of pediatric solid tumors.

Pub Date : 2025-06-06 DOI: 10.20517/cdr.2024.208 Ivan Li, Yuchen Huo, Ting Yang, Howard Gunawan, Ludmil B Alexandrov, Peter E Zage

Acquired resistance to molecularly targeted therapies for cancer.

Pub Date : 2025-06-05 DOI: 10.20517/cdr.2024.189 Nolan M Stubbs, Tyler J Roady, Maximilian P Schwermann, Elias O Eteshola, William J MacDonald, Connor Purcell, Dinara Ryspayeva, Nataliia Verovkina, Vida Tajiknia, Maryam Ghandali, Viva Voong, Alexis J Lannigan, Alexander G Raufi, Sean Lawler, Sheldon L Holder, Benedito A Carneiro, Liang Cheng, Howard P Safran, Stephanie L Graff, Don S Dizon, Sendurai A Mani, Attila A Seyhan, Robert W Sobol, Eric T Wong, Clark C Chen, Ziya Gokaslan, Martin S Taylor, Brian M Rivers, Wafik S El-Deiry

PER2 expression and cellular localization play a critical role in tumor aggressiveness and drug resistance in an in vitro model of hepatocellular carcinoma.

Pub Date : 2025-06-03 DOI: 10.20517/cdr.2024.193 Mariarosaria Negri, Feliciana Amatrudo, Donatella Paola Provvisiero, Roberta Patalano, Giovanna Trinchese, Fabiano Cimmino, Cristina de Angelis, Chiara Simeoli, Renata Simona Auriemma, Maria Pina Mollica, Annamaria Colao, Rosario Pivonello, Claudia Pivonello