Alzheimer disease and associated disorders

An Anti-tau Therapeutic Antibody Etalanetug (E2814): A Phase 1, First-in-human (FIH) Study of Single and Multiple Ascending Doses in Healthy Subjects.

Pub Date : 2025-07-17 DOI: 10.1097/WAD.0000000000000680 Sumit Rawal, Kristin R Wildsmith, Jagadeesh Aluri, Takuya Yagi, Min-Kun Chang, Hongmei Niu, Jin Zhou, Kanta Horie, Eri Takahashi, Peter Boyd, Larisa Reyderman

Correlation of Depression and Anxiety Responses on the Mild Behavioral Impairment Checklist With the Cornell Scale for Depression in Dementia and Abbreviated Version of the Penn State Worry Questionnaire.

Pub Date : 2025-04-01 DOI: 10.1097/WAD.0000000000000675 Aditya Aundhakar, Fahad Rajput, Aravind Ganesh, Zahinoor Ismail, Eric E Smith

Protocol for a Randomized Phase II/III Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Extended-Release Metformin in Amnestic Mild Cognitive Impairment: Metformin in Alzheimer Dementia Prevention (MAP).

Pub Date : 2025-04-01 DOI: 10.1097/WAD.0000000000000677 José A Luchsinger, Davangere Devanand, Terry E Goldberg, Sam Cammack, Gabriela Hernández-Santiago, Kenichi Oishi, William Jagust, Suzanne Baker, Susan Landau, Gayane Yenokyan, Joshua Betz, Stephanie Mayers, Lindsay M Eyzaguirre, Daniel Hanley