I: Experimental therapeutics – preclinical

I: Experimental therapeutics – preclinical
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I: Experimental therapeutics – preclinical - 最新文献

I14 Development of drugs against SPT4/SPT5 for the treatment of Huntington’s disease

Pub Date : 2022-09-01 DOI: 10.1136/jnnp-2022-ehdn.240 A. Bahat, R. Dikstein

I06 Allele-selective inhibition of mutant htt transcription throughout the brain after subcutaneous administration of a patrol™-enabled investigational genetic therapy in the r6/2 Huntington’s disease transgenic mouse model

Pub Date : 2022-09-01 DOI: 10.1136/jnnp-2022-ehdn.232 R. Friedlander, V. Caro, D. Carlisle, N. Monks, Dani M. Stoltzfus, Natasha L Bennett, Y. Suofu, Jinho Kim, Fang Li, Xiaomin Wang, Stacy Yeh, O. V. Baranov, S. Baranov, Barry A. Badeau, Jeremy Gleaton, Gabriel A Cintrón-Rosado, Ryan R Dyer, D. Stephan, W. R. Mann, Sandra Rojas-Caro

I13 Polyqure- inhibiton of TRMT2A to cure polyQ diseases

Pub Date : 2022-09-01 DOI: 10.1136/jnnp-2022-ehdn.239 A. Voigt, Sabine Hamm, D. Niessing
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