Toxicology and applied pharmacology

Toxicology and Applied Pharmacology publishes original scientific research of relevance to animals or humans pertaining to the action of chemicals, drugs, or chemically-defined natural products. Regular articles address mechanistic approaches to physiological, pharmacologic, biochemical, cellular, or molecular understanding of toxicologic/pathologic lesions and to methods used to describe these responses. Safety Science articles address outstanding state-of-the-art preclinical and human translational characterization of drug and chemical safety employing cutting-edge science. Highly significant Regulatory Safety Science articles will also be considered in this category. Papers concerned with alternatives to the use of experimental animals are encouraged. Short articles report on high impact studies of broad interest to readers of TAAP that would benefit from rapid publication. These articles should contain no more than a combined total of four figures and tables. Authors should include in their cover letter the justification for consideration of their manuscript as a short article.

《毒理学与应用药理学》发表与动物或人类相关的原创科学研究，研究内容涉及化学品、药物或化学定义的天然产物的作用。 常规文章涉及生理、药理、生物化学、细胞或分子对毒理/病理损伤的理解以及描述这些反应的方法的机械方法。安全科学文章涉及采用尖端科学对药物和化学品安全性进行的杰出的临床前和人体转化表征。高度重要的监管安全科学文章也将归入此类别。鼓励提交与实验动物使用替代方案有关的论文。 短文报告了对 TAAP 读者具有广泛兴趣的、影响深远的研究，这些研究将受益于快速发表。这些文章总共不应包含超过四个图表。作者应在求职信中说明将其稿件视为短文的理由。