Pragmatic and Observational Research is an international, peer-reviewed, open-access journal that publishes data from studies designed to closely reflect medical interventions in real-world clinical practice, providing insights beyond classical randomized controlled trials (RCTs). While RCTs maximize internal validity for cause-and-effect relationships, they often represent only specific patient groups. This journal aims to complement such studies by providing data that better mirrors real-world patients and the usage of medicines, thus informing guidelines and enhancing the applicability of research findings across diverse patient populations encountered in everyday clinical practice.
Pub Date : 2024-08-15DOI: 10.2147/POR.S469973Georgie M Massen, Olivia Blamires, Megan Grainger, Max Matta, Rachel Monica Gyemfuah Twumasi, Tanvi Joshi, Alex Laity, Elena Nakariakova, Thilaksana Thavaranjan, Aziz Sheikh, Jennifer K Quint