ACS Infectious Diseases

ACS Infectious Diseases will be the first journal to highlight chemistry and its role in this multidisciplinary and collaborative research area. The journal will cover a diverse array of topics including, but not limited to: * Discovery and development of new antimicrobial agents — identified through target- or phenotypic-based approaches as well as compounds that induce synergy with antimicrobials. * Characterization and validation of drug target or pathways — use of single target and genome-wide knockdown and knockouts, biochemical studies, structural biology, new technologies to facilitate characterization and prioritization of potential drug targets. * Mechanism of drug resistance — fundamental research that advances our understanding of resistance; strategies to prevent resistance. * Mechanisms of action — use of genetic, metabolomic, and activity- and affinity-based protein profiling to elucidate the mechanism of action of clinical and experimental antimicrobial agents. * Host-pathogen interactions — tools for studying host-pathogen interactions, cellular biochemistry of hosts and pathogens, and molecular interactions of pathogens with host microbiota. * Small molecule vaccine adjuvants for infectious disease. * Viral and bacterial biochemistry and molecular biology.

ACS Infectious Diseases已被以下权威数据库收录：AS, Web of Science-SCIE, Scopus。 ACS Infectious Diseases将是第一本突出化学及其在这一多学科合作研究领域的作用的期刊。期刊将涵盖各种主题，包括但不限于： * 新抗菌剂的发现和开发--通过基于靶标或表型的方法以及与抗菌剂产生协同作用的化合物进行鉴定。 * 药物靶点或途径的特征描述和验证--利用单个靶点和全基因组敲除和基因敲除、生化研究、结构生物学、新技术来促进潜在药物靶点的特征描述和优先排序。 * 耐药性机制--基础研究可增进我们对耐药性的了解；预防耐药性的战略。 * 作用机制--利用基因、代谢组学、基于活性和亲和力的蛋白质分析来阐明临床和实验抗菌剂的作用机制。 * 宿主与病原体的相互作用--研究宿主与病原体相互作用、宿主与病原体的细胞生物化学以及病原体与宿主微生物群的分子相互作用的工具。 * 用于传染病的小分子疫苗佐剂。 * 病毒和细菌的生物化学与分子生物学。