ASPET 2023 Annual Meeting Abstract - Drug Metabolism and Disposition (DMD)

Nucleotidases Exhibit Enzymatic Activities Toward the Pharmacologically Active Metabolites of Gemcitabine and Emtricitabine

Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.540660 H. Seneviratne, N. R. Phulara, C. Ishida, P. Espenshade

Managing Drug Interactions Involving the Over-the-Counter Opioid Loperamide through Physiologically Based Pharmacokinetic Modeling

Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.266210 Zhu Zhou, Mengyao Li, P. Zhao, J. Dinh, M. Paine

Deciphering the Zonal Distribution of Hepatic Drug Metabolizing Enzymes and Transporters in Mice by Single Cell Transcriptomics

Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.161490 J. Lim, C. Klaassen, J. Cui