Mechanobiology in Medicine

Three-dimensional spheroid models for cardiovascular biology and pathology

Pub Date : 2025-06-28 DOI: 10.1016/j.mbm.2025.100144 Alanna Krug , Gabrielle Inserra , Rhonda Drewes , Amanda Krajnik , Joseph A. Brazzo III , Thomas Mousso , Su Chin Heo , Yongho Bae

Causal association analysis between blood metabolomes and osteopenia and therapeutic target prediction for mechanomedicine

Pub Date : 2025-06-09 DOI: 10.1016/j.mbm.2025.100137 Ruobing Liu , Yaru Huang , Maogang Jiang , Fei Xu , Qilin Pei , Jiajun Ma , Youru Li , Siqi Shen , Bo Zhang , Xiangyang Guo , Jing Cai , Wenwen Wang

Beyond biochemical patterning: How mechanical bistability governs robust organoid morphogenesis

Pub Date : 2025-06-01 DOI: 10.1016/j.mbm.2025.100134 Qigan Gao, Yuehua Yang, Haoxiang Yang, Hongyuan Jiang