Adipocyte-derived extracellular vesicles are key regulators of central leptin sensitivity and energy homeostasis

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DOI:10.1016/j.cmet.2025.10.005
作者：Jin Wang, Xuhong Zhang, Ye Zhu, Haixiang Sun, Xuetao Chen, Zhicong Zhao, Nina Zhang, Chenyu Zhang, Liang Li, Yan Bi
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.cmet.2025.10.005

Elsevier

Abstract：The exact mechanisms underlying leptin resistance, the central mechanism of obesity, remain elusive. Herein, we demonstrate that adipocyte-derived extracellular vesicles (Ad-EVs) serve as ke

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