Modified hTERT promoters-driven purine nucleoside phosphorylase-gene therapy in association with chemo- and targeted therapy in the context of ovarian cancer

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DOI:10.1038/s41417-025-00932-6
作者：Quoc Manh Nguyen, Pierre-Fran?ois Dupré, Mathieu Berchel, Marylène Lévêque, Sylvie Choblet-Thery, Frédérique d’Arbonneau, Tristan Montier
文献类型：期刊论文
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Nature

Abstract：Ovarian cancer has the highest mortality-to-incidence ratio among gynecologic cancers worldwide. E.coli Purine Nucleoside Phosphorylase-based gene-directed enzyme prodrug therapy (PNP-GDEPT)

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