CoCrMo Particles Drive Macrophage Ferroptosis via Inhibiting the Sirtuin 1/NRF2/GPX4 Pathway to Promote Periprosthetic Inflammatory Osteolysis

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DOI:10.1021/acsbiomaterials.5c01694
作者：Guangtao Fu, , , Jielong Zhou, , , Rongjie Wu*, , , Jianling Su, , , Chuangran Wu, , , Bichun Zhang, , , Yu Xie, , , Qiujian Zheng
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Nanoscale wear particles generated over time in the implant–bone interface induce profound periprosthetic inflammatory osteolysis, the most common complication after total joint arthroplasty

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